Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | P4HB | P07237 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.37 |
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
| ▸ | F7 | P08709 | 2/20 | 0.36 |
| ▸ | F3 | P13726 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ECE1 | P42892 | 1/20 | 0.36 |
| ▸ | SGMS1 | Q86VZ5 | 1/20 | 0.36 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.36 |
| ▸ | MUS81 | Q96NY9 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9506056 | 1.00 | BACE1 (0.43) | BACE1ALDH1A1HPGDP4HBPPARA | |
| SCHEMBL9508857 | 0.99 | BACE1 (0.42) | BACE1ALDH1A1HPGDPPARAMMP2 | |
| SCHEMBL9506122 | 0.99 | BACE1 (0.42) | BACE1ALDH1A1HPGDPPARAMMP2 | |
| SCHEMBL9504740 | 0.99 | BACE1 (0.42) | BACE1ALDH1A1HPGDPPARAMMP2 | |
| SCHEMBL9506890 | 0.99 | BACE1 (0.42) | BACE1ALDH1A1HPGDPPARAMMP2 | |
| SCHEMBL9508853 | 0.99 | BACE1 (0.42) | BACE1ALDH1A1HPGDPPARAMMP2 | |
| SCHEMBL9506893 | 0.99 | BACE1 (0.42) | BACE1ALDH1A1HPGDPPARAMMP2 | |
| SCHEMBL9506118 | 0.99 | BACE1 (0.42) | BACE1ALDH1A1HPGDPPARAMMP2 | |
| SCHEMBL9504758 | 0.99 | BACE1 (0.42) | BACE1ALDH1A1HPGDPPARAMMP2 | |
| SCHEMBL27557941 | 0.83 | PPARA (0.40) | PPARAMMP2F7F3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0161939-B1 | ARYLHYDROXAMATES | E.R. Squibb & Sons, Inc. (US) | 1993-07-21 | — | — | EP | disclosed |
| US-4607053-A | L2POXYGENASE INHIBITORS | E. R. SQUIBB & SONS, INC. (US) | 1986-08-19 | — | — | US | disclosed |
| EP-0161939-A2 | Arylhydroxamates | E.R. Squibb & Sons, Inc. (US) | 1985-11-21 | — | — | EP | disclosed |