Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 2/20 | 0.50 |
| ▸ | METAP2 | P50579 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.39 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | KDM5A | P29375 | 2/20 | 0.36 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.36 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | KDM4A | O75164 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7266734 | 1.00 | METAP1 (0.50) | METAP1METAP2ALDH1A1SLC1A3SLC1A2 | |
| SCHEMBL7330492 | 0.86 | METAP1 (0.47) | METAP1METAP2ALDH1A1SLC1A3SLC1A2 | |
| SCHEMBL7268624 | 0.86 | METAP1 (0.47) | METAP1METAP2ALDH1A1SLC1A3SLC1A2 | |
| SCHEMBL3999207 | 0.85 | METAP1 (0.46) | METAP1METAP2ALDH1A1SLC1A3SLC1A2 | |
| SCHEMBL3997976 | 0.85 | METAP1 (0.46) | METAP1METAP2ALDH1A1SLC1A3SLC1A2 | |
| SCHEMBL3997942 | 0.85 | METAP1 (0.46) | METAP1METAP2ALDH1A1SLC1A3SLC1A2 | |
| SCHEMBL1162229 | 0.84 | METAP1 (0.51) | METAP1METAP2ALDH1A1SLC1A3SLC1A2 | |
| SCHEMBL18939426 | 0.84 | METAP1 (0.51) | METAP1METAP2ALDH1A1SLC1A3SLC1A2 | |
| SCHEMBL3994993 | 0.83 | METAP1 (0.44) | METAP1METAP2ALDH1A1SLC1A3SLC1A2 | |
| SCHEMBL3992081 | 0.83 | METAP1 (0.44) | METAP1METAP2ALDH1A1SLC1A3SLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0198271-B1 | PEPTIDES | MERCK PATENT GmbH (DE) | 1993-06-09 | — | — | EP | disclosed |
| US-4755592-A | Statine-containing peptides useful in medicaments | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1988-07-05 | — | — | US | disclosed |