Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 18/20 | 0.35 |
| ▸ | FLT3 | P36888 | 6/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL524079 | 0.83 | — | — | |
| SCHEMBL10195889 | 0.83 | — | — | |
| SCHEMBL524081 | 0.83 | — | — | |
| SCHEMBL524080 | 0.83 | — | — | |
| SCHEMBL8312559 | 0.79 | TSHR (0.41) | TSHRSYKFLT3AURKB | |
| SCHEMBL8312105 | 0.79 | TSHR (0.41) | TSHRSYKFLT3AURKB | |
| SCHEMBL3114403 | 0.79 | TSHR (0.41) | TSHRSYKFLT3AURKB | |
| SCHEMBL14749811 | 0.79 | — | — | |
| SCHEMBL6155366 | 0.79 | — | — | |
| SCHEMBL14671531 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2945950-B1 | ISOMANNIDE DERIVATIVES AS INHIBITORS OF SOLUBLE EPOXIDE HYDROLASE | SANOFI SA (FR) | 2017-03-01 | — | — | EP | disclosed |
| EP-0198271-B1 | PEPTIDES | MERCK PATENT GmbH (DE) | 1993-06-09 | — | — | EP | disclosed |
| US-5215966-A | For treatment of hypertension, hyperaldosteronism and cardiac insufficiency | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-06-01 | — | — | US | disclosed |
| US-4755592-A | Statine-containing peptides useful in medicaments | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1988-07-05 | — | — | US | disclosed |
| EP-0272444-A2 | Renin-inhibiting peptides | MERCK PATENT GmbH (DE) | 1988-06-29 | — | — | EP | disclosed |
| EP-0198271-A2 | Peptides | MERCK PATENT GmbH (DE) | 1986-10-22 | — | — | EP | disclosed |