⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL290910 | 0.83 | — | — | |
| Hydrochloric Acid SCHEMBL6573644 | 0.80 | — | — | |
| SCHEMBL26030 | 0.79 | — | — | |
| Ammonia Solution, Strong SCHEMBL4994633 | 0.76 | — | — | |
| Water SCHEMBL28555745 | 0.76 | — | — | |
| SCHEMBL23295170 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL1844020 | 0.76 | — | — | |
| SCHEMBL1237944 | 0.73 | TSHR (0.35) | — | |
| Methyl Alcohol SCHEMBL7117031 | 0.73 | — | — | |
| SCHEMBL8942508 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0331524-B1 | SYNTHESIS OF TRICHOSTATINS | Japan Tobacco Inc. (JP) | 1993-08-18 | — | — | EP | disclosed |
| US-4946999-A | Novel intermediates for synthesis of trichostatic acid or trichostatin A, and processes for preparing trichostatic acid and trichostatin A | JAPAN TOBACCO INC. (JP) | 1990-08-07 | — | — | US | disclosed |
| EP-0331524-A2 | Synthesis of trichostatins | Japan Tobacco Inc. (JP) | 1989-09-06 | — | — | EP | disclosed |