Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | RARB | P10826 | 5/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | RARA | P10276 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9506105 | 0.99 | KDM4E (0.52) | KDM4EALDH1A1HPGDL3MBTL1HTT | |
| SCHEMBL9506339 | 0.99 | KDM4E (0.52) | KDM4EALDH1A1HPGDL3MBTL1HTT | |
| SCHEMBL9506393 | 0.99 | KDM4E (0.52) | KDM4EALDH1A1HPGDL3MBTL1HTT | |
| SCHEMBL9507867 | 0.99 | KDM4E (0.52) | KDM4EALDH1A1HPGDL3MBTL1HTT | |
| SCHEMBL9506037 | 0.99 | KDM4E (0.52) | KDM4EALDH1A1HPGDL3MBTL1HTT | |
| SCHEMBL9507799 | 0.99 | KDM4E (0.52) | KDM4EALDH1A1HPGDL3MBTL1HTT | |
| SCHEMBL9506375 | 0.99 | KDM4E (0.52) | KDM4EALDH1A1HPGDL3MBTL1HTT | |
| SCHEMBL9506551 | 0.98 | KDM4E (0.50) | KDM4EALDH1A1HPGDL3MBTL1HTT | |
| SCHEMBL9507851 | 0.94 | KDM4E (0.45) | KDM4EALDH1A1HPGDL3MBTL1HTT | |
| SCHEMBL9618076 | 0.89 | KDM4E (0.51) | KDM4EALDH1A1HPGDL3MBTL1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0317175-B1 | PYRIMIDINE DERIVATIVES | SEIKO EPSON CORPORATION (JP) | 1993-09-22 | — | — | EP | claimed |
| EP-0317175-A2 | Pyrimidine derivatives | SEIKO EPSON CORPORATION (JP) | 1989-05-24 | — | — | EP | claimed |
| EP-0317175-B1 | PYRIMIDINE DERIVATIVES | SEIKO EPSON CORPORATION (JP) | 1993-09-22 | — | — | EP | disclosed |
| EP-0317175-A2 | Pyrimidine derivatives | SEIKO EPSON CORPORATION (JP) | 1989-05-24 | — | — | EP | disclosed |