⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9506484 | 1.00 | — | — | |
| SCHEMBL892802 | 0.78 | — | — | |
| SCHEMBL1432498 | 0.78 | — | — | |
| SCHEMBL17226453 | 0.78 | — | — | |
| SCHEMBL6671725 | 0.78 | — | — | |
| SCHEMBL24891036 | 0.76 | — | — | |
| SCHEMBL2633071 | 0.76 | — | — | |
| SCHEMBL20627927 | 0.76 | — | — | |
| SCHEMBL21933694 | 0.76 | POLB (0.41) | — | |
| SCHEMBL13948170 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0330247-B1 | N-HYDROXY-ALPHA-AMINO ACIDS, AMIDES AND OTHER DERIVATIVES THEREOF | DSM N.V. (NL) | 1993-07-07 | — | — | EP | disclosed |
| US-5101036-A | PROCESS FOR THE PREPARATION OF N-HYDROXY-ALPHA-AMINO ACID AMIDES | STAMICARBON B.V. (NL) | 1992-03-31 | — | — | US | disclosed |
| US-5072041-A | OPTICALLY ACTIVE N-HYDROXY-ALPHA-AMINO ACIDS, AMIDES AND THEIR DERIVATIVES | STAMICARBON B.V. (NL) | 1991-12-10 | — | — | US | disclosed |
| EP-0330247-A1 | N-hydroxy-alpha-amino acids, amides and other derivatives thereof | DSM N.V. (NL) | 1989-08-30 | — | — | EP | disclosed |