Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR5A1 | Q13285 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 4/20 | 0.42 |
| ▸ | THRA | P10827 | 3/20 | 0.38 |
| ▸ | THRB | P10828 | 3/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.37 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9502553 | 1.00 | NR5A1 (0.43) | NR5A1ESR1THRATHRBLTA4H | |
| SCHEMBL9503380 | 1.00 | NR5A1 (0.43) | NR5A1ESR1THRATHRBLTA4H | |
| SCHEMBL9504380 | 1.00 | NR5A1 (0.43) | NR5A1ESR1THRATHRBLTA4H | |
| SCHEMBL10336389 | 1.00 | NR5A1 (0.43) | NR5A1ESR1THRATHRBLTA4H | |
| SCHEMBL9502646 | 1.00 | NR5A1 (0.43) | NR5A1ESR1THRATHRBLTA4H | |
| SCHEMBL9502690 | 0.98 | ESR1 (0.44) | NR5A1ESR1THRATHRBLTA4H | |
| SCHEMBL9504300 | 0.93 | ESR1 (0.49) | NR5A1ESR1THRATHRBLTA4H | |
| SCHEMBL9503306 | 0.85 | ESR1 (0.40) | ESR1LTA4H | |
| SCHEMBL9685171 | 0.83 | NR5A1 (0.44) | NR5A1THRATHRBLTA4H | |
| SCHEMBL9684782 | 0.83 | NR5A1 (0.44) | NR5A1THRATHRBLTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0364548-B1 | OCTAFLUOROBIPHENYLS | MERCK PATENT GmbH (DE) | 1993-06-09 | — | — | EP | disclosed |
| EP-0364548-A1 | OCTAFLUOROBIPHENYLS. | MERCK PATENT GMBH (DE) | 1990-04-25 | — | — | EP | disclosed |
| WO-1989009203-A1 | OCTAFLUOROBIPHENYLS | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1989-10-05 | — | — | WO | disclosed |