Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.35 |
| ▸ | CCR2 | P41597 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9506596 | 1.00 | MEN1 (0.40) | MEN1KMT2AMAPTGAACYP2C9 | |
| SCHEMBL9763620 | 0.98 | MAPT (0.40) | MEN1KMT2AMAPTGAACYP2C9 | |
| SCHEMBL9763556 | 0.98 | MAPT (0.40) | MEN1KMT2AMAPTGAACYP2C9 | |
| SCHEMBL7573131 | 0.98 | MAPT (0.40) | MEN1KMT2AMAPTGAACYP2C9 | |
| SCHEMBL9763968 | 0.98 | MAPT (0.40) | MEN1KMT2AMAPTGAACYP2C9 | |
| SCHEMBL9763974 | 0.98 | MAPT (0.40) | MEN1KMT2AMAPTGAACYP2C9 | |
| SCHEMBL7511813 | 0.98 | MEN1 (0.39) | MEN1KMT2AMAPTGAACYP2C9 | |
| SCHEMBL8452712 | 0.98 | MEN1 (0.39) | MEN1KMT2AMAPTGAACYP2C9 | |
| SCHEMBL7514371 | 0.98 | MAPT (0.40) | MEN1KMT2AMAPTGAACYP2C9 | |
| SCHEMBL9763613 | 0.98 | MAPT (0.40) | MEN1KMT2AMAPTGAACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2233626-A | — | — | None | — | — | JP | disclosed |
| EP-0387032-B1 | TRIFLUOROBENZENE DERIVATIVES AND LIQUID CRYSTAL COMPOSITIONS CONTAINING THE SAME | CHISSO CORP (JP) | 1993-06-16 | — | — | EP | disclosed |
| US-5032313-A | Trifluorobenzene derivative and liquid crystal composition containing the same | CHISSO CORPORATION (JP) | 1991-07-16 | — | — | US | disclosed |
| JP-H02233626-A | TRIFLUOROBENZENE DERIVATIVE | CHISSO CORP | 1990-09-17 | — | — | JP | disclosed |
| EP-0387032-A1 | Trifluorobenzene derivatives and liquid crystal compositions containing the same | Chisso Corporation (JP) | 1990-09-12 | — | — | EP | disclosed |