⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9868792 | 0.76 | — | — | |
| SCHEMBL13780277 | 0.74 | — | — | |
| SCHEMBL10959093 | 0.73 | MAPK1 (0.54) | — | |
| SCHEMBL9104 | 0.73 | KDM4E (0.46) | — | |
| SCHEMBL10959966 | 0.72 | KDM4E (0.58) | — | |
| SCHEMBL1832048 | 0.70 | — | — | |
| SCHEMBL4243347 | 0.69 | — | — | |
| SCHEMBL28334441 | 0.69 | — | — | |
| SCHEMBL18412201 | 0.68 | HCAR2 (0.42) | — | |
| SCHEMBL6197044 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0278911-B1 | BICYCLIC BETA-LACTAM CARBOXYLIC ACIDS | CIBA-GEIGY AG (CH) | 1993-08-04 | — | — | EP | disclosed |
| US-4965260-A | PENICILLINS | CIBA-GEIGY CORPORATION (US) | 1990-10-23 | — | — | US | disclosed |
| EP-0297042-A1 | Substituted penem compounds | CIBA-GEIGY AG (CH) | 1988-12-28 | — | — | EP | disclosed |
| EP-0278911-A1 | Bicyclic beta-lactam carboxylic acids | CIBA-GEIGY AG (CH) | 1988-08-17 | — | — | EP | disclosed |
| EP-0233155-A1 | Aminoacyloxymethyl compounds | CIBA-GEIGY AG (CH) | 1987-08-19 | — | — | EP | disclosed |
| EP-0201459-A1 | Acylaminomethyl-penem compounds, their preparation and pharmaceutical formulations containing them | CIBA-GEIGY AG (CH) | 1986-11-12 | — | — | EP | disclosed |
| EP-0171362-A1 | Aminoalkyl penem compounds | CIBA-GEIGY AG (CH) | 1986-02-12 | — | — | EP | disclosed |
| US-4214094-A | ANTILIPEMIC AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-07-22 | — | — | US | disclosed |