Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 8/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.47 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.46 |
| ▸ | CFTR | P13569 | 1/20 | 0.44 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TYMS | P04818 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30882673 | 0.79 | CFTR (0.48) | SMN1; SMN2NPSR1CYP2C19CYP2C9MEN1 | |
| SCHEMBL675984 | 0.79 | CFTR (0.48) | SMN1; SMN2NPSR1CYP2C19CYP2C9MEN1 | |
| SCHEMBL3887315 | 0.77 | SMN1; SMN2 (1.00) | SMN1; SMN2NPSR1CYP2C19CYP2C9MEN1 | |
| SCHEMBL11498604 | 0.77 | NPSR1 (0.51) | SMN1; SMN2NPSR1CYP2C19CYP2C9MEN1 | |
| SCHEMBL12134500 | 0.74 | MAPT (0.47) | SMN1; SMN2NPSR1CYP2C19CYP2C9MEN1 | |
| SCHEMBL10649373 | 0.73 | SMN1; SMN2 (0.42) | SMN1; SMN2MEN1KMT2AL3MBTL1TDP1 | |
| SCHEMBL8577386 | 0.73 | SMN1; SMN2 (0.43) | SMN1; SMN2NPSR1CYP2C19CYP2C9MEN1 | |
| SCHEMBL28455989 | 0.73 | NPSR1 (0.63) | SMN1; SMN2NPSR1CYP2C19CYP2C9MEN1 | |
| SCHEMBL9506747 | 0.72 | NPSR1 (0.58) | SMN1; SMN2NPSR1CYP2C19CYP2C9MEN1 | |
| SCHEMBL6739516 | 0.72 | SMN1; SMN2 (0.50) | SMN1; SMN2NPSR1CYP2C19CYP2C9MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0377406-B1 | PRESSURE-SENSITIVE OR HEAT-SENSITIVE RECORDING MATERIAL | CIBA-GEIGY AG (CH) | 1993-06-09 | — | — | EP | disclosed |
| US-5013707-A | Pressure- or heat-sensitive recording material | CIBA-GEIGY CORPORATION (US) | 1991-05-07 | — | — | US | disclosed |
| EP-0377406-A1 | Pressure-sensitive or heat-sensitive recording material | CIBA-GEIGY AG (CH) | 1990-07-11 | — | — | EP | disclosed |