⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24245454 | 0.82 | — | — | |
| SCHEMBL27383471 | 0.78 | — | — | |
| SCHEMBL27609361 | 0.76 | — | — | |
| SCHEMBL9499226 | 0.76 | EPHX1 (0.48) | — | |
| SCHEMBL9349578 | 0.76 | EPHX1 (0.48) | — | |
| SCHEMBL28180308 | 0.76 | EPHX1 (0.48) | — | |
| SCHEMBL27600186 | 0.76 | EPHX1 (0.48) | — | |
| SCHEMBL331659 | 0.74 | — | — | |
| SCHEMBL484336 | 0.74 | — | — | |
| SCHEMBL977724 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2509949-B1 | PYRIDINONE HYDROXYCYCLOPENTYL CARBOXAMIDES: HIV INTEGRASE INHIBITORS WITH THERAPEUTIC APPLICATIONS | UNIV GEORGIA (US) | 2014-04-23 | — | — | EP | claimed |
| EP-0248217-B1 | USE OF ORNITHINE DECARBOXYLASE INHIBITOR FOR PREPARING A MEDICAMENT FOR USE IN THE TREATMENT, IN CONJUCTION WITH LAK CELLS AND INTERLEUKIN-2, OF TUMORS | MERRELL DOW PHARMACEUTICALS INC. (US) | 1993-07-28 | — | — | EP | claimed |
| EP-0288055-B1 | USE OF ODC INHIBITORS, DACARBAZINE, AND INTERFERON, IN THE TREATMENT OF MALIGNANT MELANOMA | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-07-15 | — | — | EP | claimed |