SCHEMBL9507152

SCHEMBL9507152

CC(=O)Oc1ccc(C(=O)OC(=O)c2ccccc2)cc1

nearest known ligand 0.76

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ELANE P08246 6/20 0.76
HSD17B10 Q99714 1/20 0.58
MAPT P10636 4/20 0.56
TDP1 Q9NUW8 2/20 0.56
ALDH1A1 P00352 2/20 0.56
GAA P10253 2/20 0.56
HSP90AA1 P07900 1/20 0.56
PARP10 Q53GL7 1/20 0.56
KMT2A Q03164 2/20 0.56
MEN1 O00255 1/20 0.56
L3MBTL1 Q9Y468 1/20 0.53
PKM P14618 1/20 0.53
LMNA P02545 2/20 0.53
MAPK1 P28482 1/20 0.53
PTGS2 P35354 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10863256 0.96 ELANE (0.71) ELANEHSD17B10MAPTTDP1ALDH1A1
SCHEMBL9507144 0.92 ELANE (0.62) ELANEHSD17B10MAPTTDP1ALDH1A1
SCHEMBL16429669 0.91 ELANE (0.79) ELANEHSD17B10MAPTTDP1ALDH1A1
SCHEMBL16705193 0.89 ELANE (0.75) ELANEHSD17B10MAPTTDP1ALDH1A1
SCHEMBL6054677 0.87 ELANE (0.72) ELANEHSD17B10MAPTTDP1ALDH1A1
SCHEMBL16429666 0.87 ELANE (0.72) ELANEHSD17B10MAPTTDP1ALDH1A1
SCHEMBL5676789 0.86 PARP10 (0.72) ELANEHSD17B10MAPTTDP1ALDH1A1
SCHEMBL5864662 0.86 ELANE (0.60) ELANEHSD17B10MAPTTDP1ALDH1A1
SCHEMBL1590016 0.86 ELANE (1.00) ELANEHSD17B10MAPTTDP1ALDH1A1
SCHEMBL9356185 0.86 ELANE (0.56) ELANEHSD17B10MAPTTDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4892912-A DEPOLYMERIZATION THEN POLYMERIZING FRAGMENTS, ELASTICITY, MECHANICAL STRENGTH IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1990-01-09 US claimed
EP-0321691-B1 PROCESS FOR PRODUCING AROMATIC POLYESTER IDEMITSU PETROCHEMICAL CO. LTD. (JP) 1993-09-29 EP disclosed
US-4892912-A DEPOLYMERIZATION THEN POLYMERIZING FRAGMENTS, ELASTICITY, MECHANICAL STRENGTH IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1990-01-09 US disclosed
EP-0321691-A2 Process for producing aromatic polyester IDEMITSU PETROCHEMICAL CO. LTD. (JP) 1989-06-28 EP disclosed