Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9756105 | 0.97 | KMT2A (0.51) | KMT2AGAAHPGDSMN1; SMN2RAB9A | |
| SCHEMBL9756491 | 0.96 | KMT2A (0.50) | KMT2AGAAHPGDSMN1; SMN2RAB9A | |
| SCHEMBL9755856 | 0.96 | KMT2A (0.50) | KMT2AGAAHPGDSMN1; SMN2RAB9A | |
| SCHEMBL9755861 | 0.96 | KMT2A (0.50) | KMT2AGAAHPGDSMN1; SMN2RAB9A | |
| SCHEMBL9756082 | 0.94 | POLB (0.50) | HPGDSMN1; SMN2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL9755963 | 0.86 | POLB (0.61) | KMT2ASMN1; SMN2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL9756160 | 0.83 | POLB (0.61) | KMT2AHPGDSMN1; SMN2CYP3A4CYP2C9 | |
| SCHEMBL9756366 | 0.82 | POLB (0.60) | KMT2AHPGDSMN1; SMN2CYP3A4CYP2C9 | |
| SCHEMBL8173463 | 0.82 | POLB (0.60) | KMT2AHPGDSMN1; SMN2CYP3A4CYP2C9 | |
| SCHEMBL9755967 | 0.82 | POLB (0.60) | KMT2AHPGDSMN1; SMN2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0361645-B1 | ORGANIC HYDRAZINE DERIVATIVES FOR PHARMACEUTICAL USE | ROHM AND HAAS COMPANY (US) | 1993-09-29 | — | — | EP | disclosed |
| EP-0234944-B1 | INSECTICIDAL N'-SUBSTITUTED-N-ACYL-N'-ALKYLCARBONYLHYDRAZINES | ROHM AND HAAS COMPANY (US) | 1991-04-10 | — | — | EP | disclosed |
| EP-0232075-B1 | INSECTICIDAL N'-SUBSTITUTED-N-ALKYLCARBONYL-N'-ACYL HYDRAZINES | ROHM AND HAAS COMPANY (US) | 1991-03-13 | — | — | EP | disclosed |
| EP-0361645-A2 | Organic hydrazine derivatives for pharmaceutical use | ROHM AND HAAS COMPANY (US) | 1990-04-04 | — | — | EP | disclosed |
| EP-0232075-A1 | Insecticidal N'-substituted-N-alkylcarbonyl-N'-acyl hydrazines | ROHM AND HAAS COMPANY (US) | 1987-08-12 | — | — | EP | disclosed |