Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8174684 | 0.91 | POLB (0.71) | POLBCYP3A4CYP2C9 | |
| SCHEMBL8167155 | 0.87 | POLB (0.61) | POLBCYP3A4CYP2C9 | |
| Halofenozide SCHEMBL55120 | 0.86 | POLB (0.82) | POLBCYP3A4CYP2C9 | |
| SCHEMBL4150390 | 0.86 | POLB (0.82) | POLBCYP3A4CYP2C9 | |
| SCHEMBL9826006 | 0.82 | ABCB1 (0.60) | POLB | |
| SCHEMBL9756137 | 0.79 | POLB (0.53) | POLBCYP3A4CYP2C9 | |
| SCHEMBL9714227 | 0.79 | POLB (0.71) | POLBCYP3A4CYP2C9 | |
| Halofenozide SCHEMBL28789879 | 0.79 | POLB (0.70) | POLBCYP3A4CYP2C9 | |
| SCHEMBL27433978 | 0.79 | POLB (0.62) | POLBCYP3A4CYP2C9 | |
| Hydrochloric Acid SCHEMBL8178964 | 0.78 | POLB (0.69) | POLBCYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0361645-B1 | ORGANIC HYDRAZINE DERIVATIVES FOR PHARMACEUTICAL USE | ROHM AND HAAS COMPANY (US) | 1993-09-29 | — | — | EP | disclosed |
| EP-0236618-B1 | INSECTICIDAL N'-SUBSTITUTED-N,N'-DIACYLHYDRAZINES | ROHM AND HAAS COMPANY (US) | 1991-02-27 | — | — | EP | disclosed |
| EP-0361645-A2 | Organic hydrazine derivatives for pharmaceutical use | ROHM AND HAAS COMPANY (US) | 1990-04-04 | — | — | EP | disclosed |