⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL23217312 | 0.97 | — | — | |
| SCHEMBL18773951 | 0.80 | — | — | |
| SCHEMBL2527818 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL15400491 | 0.74 | — | — | |
| Diethylamine SCHEMBL8068556 | 0.74 | — | — | |
| SCHEMBL10833596 | 0.73 | — | — | |
| SCHEMBL5782786 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL2159989 | 0.71 | TP53 (0.35) | — | |
| SCHEMBL15047215 | 0.71 | — | — | |
| Diethylamine SCHEMBL4638279 | 0.69 | TP53 (0.57) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117510471-B | Abeli synthesis method | 江苏天士力帝益药业有限公司 | 2025-02-25 | — | — | CN | disclosed |
| CN-117510471-A | Abeli synthesis method | 江苏天士力帝益药业有限公司 | 2024-02-06 | — | — | CN | disclosed |
| CN-106518808-A | 3-(N, N-disubstituted amino) propanamide derivative and preparation method and use thereof in medicine | 沈阳药科大学 | 2017-03-22 | — | — | CN | disclosed |
| CN-105833791-A | Surfactant containing o-nitrobenzyl ester photodegradation group and preparation method thereof | 大连理工大学 | 2016-08-10 | — | — | CN | disclosed |
| US-20150087886-A1 | NOVEL BIFUNCTIONAL METNASE/INTNASE INHIBITORS AND RELATED COMPOSITIONS AND METHODS OF TREATMENT OF CANCER | THE REGENTS OF THE UNIVERSITY OF NEW MEXICO | 2015-03-26 | — | — | US | disclosed |
| US-8889689-B2 | Bifunctional metnase/intnase inhibitors and related compositions and methods of treatment of cancer | STC.UNM (US) | 2014-11-18 | — | — | US | disclosed |
| US-20120302582-A1 | NOVEL BIFUNCTIONAL METNASE/INTNASE INHIBITORS AND RELATED COMPOSITIONS AND METHODS OF TREATMENT OF CANCER | THE REGENTS OF THE UNIVERSITY OF NEW MEXICO | 2012-11-29 | — | — | US | disclosed |
| EP-0376151-B1 | PROCESS FOR DYEING TEXTILE MATERIALS WITH PIGMENT DYES | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-08-25 | — | — | EP | disclosed |
| EP-0376151-A2 | Process for dyeing textile materials with pigment dyes | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-07-04 | — | — | EP | disclosed |