Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A2 | P43004 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | BTK | Q06187 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | ARG1 | P05089 | 3/20 | 0.30 |
| ▸ | ARG2 | P78540 | 1/20 | 0.30 |
| ▸ | PPM1B | O75688 | 1/20 | 0.30 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24039255 | 0.84 | MAPK1 (0.37) | SLC1A2HRH3MAPK1RECQL | |
| SCHEMBL27341351 | 0.81 | SLC1A2 (0.52) | SLC1A2MEN1BLMKMT2AARG1 | |
| SCHEMBL3427826 | 0.77 | SLC1A2 (0.58) | SLC1A2HRH3MEN1BLMKMT2A | |
| SCHEMBL17756064 | 0.77 | SLC1A2 (0.58) | SLC1A2HRH3MEN1BLMKMT2A | |
| SCHEMBL5728913 | 0.77 | MAPK1 (0.37) | SLC1A2HRH3MAPK1RECQL | |
| SCHEMBL630081 | 0.76 | SLC1A2 (0.49) | SLC1A2MEN1BLMKMT2ABTK | |
| SCHEMBL2677786 | 0.76 | CHRM2 (0.35) | SLC1A2HRH3MAPK1RECQL | |
| SCHEMBL4429527 | 0.76 | CHRM2 (0.35) | SLC1A2HRH3MAPK1RECQL | |
| SCHEMBL6861278 | 0.76 | CHRM2 (0.35) | SLC1A2HRH3MAPK1RECQL | |
| SCHEMBL27190337 | 0.74 | MEN1 (0.61) | SLC1A2MEN1BLMKMT2ABTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0557375-A1 | NEW HETEROCYCLIC COMPOUNDS AS ANTAGONISTS OF EXCITATORY AMINO ACID RECEPTORS, PROCESSES FOR THEIR PREPARATION AND THEIR USE | Astra Aktiebolag (SE) | 1993-09-01 | — | — | EP | disclosed |
| WO-1992008724-A1 | NEW HETEROCYCLIC COMPOUNDS AS ANTAGONISTS OF EXCITATORY AMINO ACID RECEPTORS, PROCESSES FOR THEIR PREPARATION AND THEIR USE | AKTIEBOLAGET ASTRA (SE) | 1992-05-29 | — | — | WO | disclosed |