Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRR1 | P24046 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.32 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.32 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.32 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.32 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9509883 | 0.80 | ACE2 (0.46) | GABRR1CYP1A2BLMACE2LTA4H | |
| SCHEMBL6383285 | 0.80 | GABRR1 (0.48) | GABRR1CYP1A2BLMACE2LTA4H | |
| SCHEMBL9509867 | 0.77 | ACE2 (0.46) | GABRR1CYP1A2BLMACE2LTA4H | |
| SCHEMBL6381215 | 0.77 | ACE2 (0.46) | GABRR1CYP1A2BLMACE2LTA4H | |
| SCHEMBL9511091 | 0.77 | ACE2 (0.46) | GABRR1CYP1A2BLMACE2LTA4H | |
| SCHEMBL6886394 | 0.76 | GABRR1 (0.38) | GABRR1CYP1A2BLMTSHRFOLH1 | |
| SCHEMBL6886391 | 0.76 | GABRR1 (0.38) | GABRR1CYP1A2BLMTSHRFOLH1 | |
| SCHEMBL6886393 | 0.76 | GABRR1 (0.38) | GABRR1CYP1A2BLMTSHRFOLH1 | |
| SCHEMBL5139179 | 0.75 | GABRR1 (0.72) | GABRR1CYP1A2BLMACE2LTA4H | |
| Hydrochloric Acid SCHEMBL9507458 | 0.75 | ACE2 (0.44) | GABRR1CYP1A2BLMACE2LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0388960-B1 | OPTICALLY ACTIVE COMPOUNDS AND THEIR PREPARATION AND USE | HITACHI, LTD. (JP) | 1993-10-06 | — | — | EP | disclosed |
| US-5152919-A | Stability, chemical resistance, high speed response, large spo ntaneous polarization, molecular orientation and wide temperat ure range | HITACHI, LTD. (JP) | 1992-10-06 | — | — | US | disclosed |
| EP-0388960-A1 | Optically active compounds and their preparation and use | HITACHI, LTD. (JP) | 1990-09-26 | — | — | EP | disclosed |