Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.52 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9703065 | 1.00 | ACE2 (0.52) | ACE2GABRR1CYP1A2BLMCA2 | |
| SCHEMBL10512732 | 1.00 | ACE2 (0.52) | ACE2GABRR1CYP1A2BLMCA2 | |
| SCHEMBL6429525 | 1.00 | ACE2 (0.52) | ACE2GABRR1CYP1A2BLMCA2 | |
| SCHEMBL9507340 | 0.94 | ACE2 (0.55) | ACE2GABRR1CYP1A2BLMGPR84 | |
| SCHEMBL9511184 | 0.93 | ACE2 (0.58) | ACE2GPR84FFAR1EPHX2MAPT | |
| SCHEMBL9507776 | 0.93 | ACE2 (0.58) | ACE2GPR84FFAR1EPHX2MAPT | |
| SCHEMBL9508668 | 0.93 | ACE2 (0.58) | ACE2GPR84FFAR1EPHX2MAPT | |
| SCHEMBL9507391 | 0.93 | ACE2 (0.58) | ACE2GPR84FFAR1EPHX2MAPT | |
| SCHEMBL9508028 | 0.93 | ACE2 (0.58) | ACE2GPR84FFAR1EPHX2MAPT | |
| SCHEMBL6381215 | 0.88 | ACE2 (0.46) | ACE2GABRR1CYP1A2BLMCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0388960-B1 | OPTICALLY ACTIVE COMPOUNDS AND THEIR PREPARATION AND USE | HITACHI, LTD. (JP) | 1993-10-06 | — | — | EP | disclosed |
| EP-0388960-A1 | Optically active compounds and their preparation and use | HITACHI, LTD. (JP) | 1990-09-26 | — | — | EP | disclosed |