SCHEMBL9507701

SCHEMBL9507701

N#Cc1c(Cl)c(Cl)c(C#N)c2c1Oc1cc(Cl)c(Cl)cc1S2

nearest known ligand 0.38

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
AHR P35869 7/20 0.38
FLT1 P17948 1/20 0.31
MEN1 O00255 1/20 0.31
ALDH1A1 P00352 1/20 0.31
TP53 P04637 1/20 0.31
CYP3A4 P08684 1/20 0.31
MAPT P10636 1/20 0.31
HPGD P15428 1/20 0.31
MAPK1 P28482 1/20 0.31
KMT2A Q03164 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6003668 0.70 AHR (0.60) AHRFLT1MEN1ALDH1A1TP53
SCHEMBL9511385 0.68 AHR (0.60) AHRFLT1
SCHEMBL9511376 0.65 AHR (0.39) AHRFLT1ALDH1A1MAPK1
SCHEMBL9508070 0.65 AHR (0.40) AHRFLT1
SCHEMBL9508159 0.64 AHR (0.36) AHRMEN1ALDH1A1CYP3A4MAPT
SCHEMBL9508164 0.64 AHR (0.50) AHRFLT1CYP3A4
SCHEMBL9510055 0.62 AHR (0.33) AHR
SCHEMBL9510063 0.61 AHR (0.36) AHRFLT1
SCHEMBL9511203 0.60 AHR (0.34) AHRFLT1
SCHEMBL5860599 0.59 AHR (0.46) AHRFLT1ALDH1A1CYP3A4HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0399293-B1 PROCESS FOR PREPARING 2-CHLORO-4-NITRO-ALKYLBENZENE BAYER AG (DE) 1993-09-01 EP disclosed
US-5095157-A Friedel-crafts catalyst BAYER AKTIENGESELLSCHAFT (DE) 1992-03-10 US disclosed
EP-0399293-A1 Process for preparing 2-chloro-4-nitro-alkylbenzene BAYER AG (DE) 1990-11-28 EP disclosed