Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL9507833

COC(=O)CN(CCN(CC(=O)OC)CC(=O)OC)CC(=O)OC.N

nearest known ligand 0.46

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.46
KMT2A Q03164 2/20 0.44
MEN1 O00255 1/20 0.44
TDP1 Q9NUW8 2/20 0.43
EYA2 O00167 1/20 0.43
APP P05067 1/20 0.43
ACE P12821 1/20 0.43
HSD17B10 Q99714 3/20 0.42
KDM4E B2RXH2 3/20 0.42
LMNA P02545 3/20 0.42
BLM P54132 2/20 0.42
PMP22 Q01453 2/20 0.42
ALOX15 P16050 2/20 0.42
MGAM O43451 1/20 0.42
GAA P10253 1/20 0.42
SI P14410 1/20 0.42
MGAM2 Q2M2H8 1/20 0.42
CHRM2 P08172 1/20 0.42
ADRA2A P08913 1/20 0.42
DRD1 P21728 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL338996 0.97 TSHR (0.48) TSHRKMT2AMEN1TDP1EYA2
SCHEMBL15746848 0.95 TSHR (0.48) TSHRKMT2AMEN1TDP1EYA2
SCHEMBL9140638 0.95 TSHR (0.48) TSHRKMT2AMEN1TDP1EYA2
Ammonia Solution, Strong SCHEMBL10726609 0.91 TDP1 (0.61) TSHRKMT2AMEN1TDP1EYA2
SCHEMBL19760043 0.88 MGAM (0.48) TSHRKMT2AMEN1TDP1EYA2
SCHEMBL5852270 0.88 TDP1 (0.64) TSHRKMT2AMEN1TDP1EYA2
SCHEMBL5852235 0.88 TDP1 (0.64) TSHRKMT2AMEN1TDP1EYA2
SCHEMBL5085940 0.88 TDP1 (0.64) TSHRKMT2AMEN1TDP1EYA2
SCHEMBL13129733 0.88 TDP1 (0.64) TSHRKMT2AMEN1TDP1EYA2
Sulfuric Acid SCHEMBL16714024 0.88 TSHR (0.40) TSHRKMT2AMEN1TDP1EYA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0245016-B1 METALLIZED POLYMERS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-09-08 EP disclosed
US-4775556-A INJECTION A STORED CHARGE INTO POLYMER SURFACE, MASKING, REDUCING METAL WITH STORED CHANGE MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1988-10-04 US disclosed
US-4710403-A DIFFUSING A METAL ION SOLUTION INTO A POLYIMIDE, REDUCING THE POLYMER; CONTACTING WITH SECOND SOLUTION TO FORM TRANSITION METAL FILM MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1987-12-01 US disclosed
EP-0245016-A2 Metallized polymers MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1987-11-11 EP disclosed