Styrene

Styrene

SCHEMBL9507947

C=CC(=O)O.C=Cc1ccccc1.CC=C(C)C(=O)O

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 1/20 0.53
ALDH1A1 P00352 2/20 0.50
TSHR P16473 2/20 0.50
HTT P42858 1/20 0.45
TDP1 Q9NUW8 2/20 0.40
GLA P06280 1/20 0.40
AKT1 P31749 1/20 0.38
HDAC3 O15379 1/20 0.38
TNKS O95271 1/20 0.38
HDAC4 P56524 1/20 0.38
HDAC1 Q13547 1/20 0.38
HCAR2 Q8TDS4 1/20 0.38
HDAC7 Q8WUI4 1/20 0.38
HDAC2 Q92769 1/20 0.38
HDAC10 Q969S8 1/20 0.38
HDAC11 Q96DB2 1/20 0.38
HDAC8 Q9BY41 1/20 0.38
TNKS2 Q9H2K2 1/20 0.38
HDAC6 Q9UBN7 1/20 0.38
HDAC9 Q9UKV0 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL4699041 0.97 AKR1C3 (0.50) AKR1C3ALDH1A1TSHRHTTTDP1
Styrene SCHEMBL134355 0.94 AKR1C3 (0.59) AKR1C3ALDH1A1TSHRHTTTDP1
Styrene SCHEMBL238869 0.94 AKR1C3 (0.59) AKR1C3ALDH1A1TSHRHTTTDP1
Styrene SCHEMBL7550251 0.91 AKR1C3 (0.52) AKR1C3ALDH1A1TSHRHTTTDP1
Styrene SCHEMBL11043969 0.91 AKR1C3 (0.55) AKR1C3ALDH1A1TSHRHTTTDP1
Styrene SCHEMBL1126458 0.91 AKR1C3 (0.55) AKR1C3ALDH1A1TSHRHTTTDP1
Styrene SCHEMBL93464 0.91 AKR1C3 (0.55) AKR1C3ALDH1A1TSHRHTTTDP1
Styrene SCHEMBL5669174 0.89 AKR1C3 (0.53) AKR1C3ALDH1A1TSHRHTTTDP1
Styrene SCHEMBL6373593 0.88 AKR1C3 (0.42) AKR1C3ALDH1A1TSHRHTTTDP1
Styrene SCHEMBL11433472 0.88 AKR1C3 (0.52) AKR1C3ALDH1A1TSHRHTTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0291315-B1 HEAT-SENSITIVE RECORDING PAPER FUJI PHOTO FILM CO., LTD. (JP) 1993-08-11 EP claimed
US-4904635-A THERMOPLASTIC RESIN AND BINDER SUBBING LAYER; UNIFORMITY, DOT REPRODUCIBILITY FUJI PHOTO FILM CO., LTD. (JP) 1990-02-27 US claimed
EP-0291315-A2 Heat-sensitive recording paper FUJI PHOTO FILM CO., LTD. (JP) 1988-11-17 EP claimed