Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYSLTR2 | Q9NS75 | 6/20 | 0.39 |
| ▸ | CYSLTR1 | Q9Y271 | 6/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6535285 | 0.93 | TSHR (0.43) | TSHRCYSLTR2CYSLTR1GABRA1GABRB2 | |
| SCHEMBL6535240 | 0.93 | TSHR (0.43) | TSHRCYSLTR2CYSLTR1GABRA1GABRB2 | |
| SCHEMBL6534841 | 0.91 | TSHR (0.44) | TSHRCYSLTR2CYSLTR1GABRA1GABRB2 | |
| SCHEMBL6534892 | 0.86 | TSHR (0.46) | TSHRCYSLTR2CYSLTR1GABRA1GABRB2 | |
| SCHEMBL984167 | 0.85 | TSHR (0.50) | TSHRCYSLTR2CYSLTR1GABRA1GABRB2 | |
| SCHEMBL982098 | 0.85 | TSHR (0.50) | TSHRCYSLTR2CYSLTR1GABRA1GABRB2 | |
| SCHEMBL983265 | 0.85 | TSHR (0.50) | TSHRCYSLTR2CYSLTR1GABRA1GABRB2 | |
| SCHEMBL983333 | 0.85 | TSHR (0.50) | TSHRCYSLTR2CYSLTR1GABRA1GABRB2 | |
| SCHEMBL981726 | 0.85 | TSHR (0.50) | TSHRCYSLTR2CYSLTR1GABRA1GABRB2 | |
| SCHEMBL983633 | 0.85 | TSHR (0.50) | TSHRCYSLTR2CYSLTR1GABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0282433-B1 | AUTOSYNERGISTIC PHENOLIC ANTIOXIDANT REACTION PRODUCT | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1993-08-11 | — | — | EP | disclosed |
| EP-0282433-A2 | Autosynergistic phenolic antioxidant reaction product | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1988-09-14 | — | — | EP | disclosed |
| US-4707300-A | PHENOLIC RESINS MODIFIED WITH MERCAPTAINS | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1987-11-17 | — | — | US | disclosed |