Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | DRD3 | P35462 | 2/20 | 0.40 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | PTGES | O14684 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | GLS | O94925 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27799490 | 0.93 | TAAR1 (0.43) | TAAR1DRD2DRD3NAAAHPGD | |
| SCHEMBL27467730 | 0.88 | TAAR1 (0.54) | TAAR1DRD2DRD3NAAAHPGD | |
| SCHEMBL19578597 | 0.86 | TAAR1 (0.52) | TAAR1DRD2DRD3NAAAGLS | |
| SCHEMBL3277114 | 0.86 | TAAR1 (0.52) | TAAR1DRD2DRD3NAAAGLS | |
| SCHEMBL2382082 | 0.86 | TAAR1 (0.52) | TAAR1DRD2DRD3NAAAGLS | |
| SCHEMBL23094089 | 0.86 | TAAR1 (0.52) | TAAR1DRD2DRD3NAAAGLS | |
| SCHEMBL3284129 | 0.86 | TAAR1 (0.52) | TAAR1DRD2DRD3NAAAGLS | |
| SCHEMBL16760660 | 0.86 | TAAR1 (0.52) | TAAR1DRD2DRD3NAAAGLS | |
| SCHEMBL8945514 | 0.85 | TAAR1 (0.36) | TAAR1DRD2DRD3HPGD | |
| SCHEMBL868922 | 0.84 | TAAR1 (0.54) | TAAR1DRD2DRD3NAAAGLS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0322164-B1 | ETHANOLAMINE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1993-09-22 | — | — | EP | disclosed |
| US-5039697-A | Adrenergic stimulants, bronchodilators | GLAXO GROUP LIMITED (GB) | 1991-08-13 | — | — | US | disclosed |
| US-5032609-A | Ethanolamine derivatives | GLAXO GROUP LIMITED (GB) | 1991-07-16 | — | — | US | disclosed |
| US-5002966-A | Adrenergic Stimulants | GLAXO GROUP LIMITED (GB) | 1991-03-26 | — | — | US | disclosed |
| EP-0322164-A2 | Ethanolamine derivatives | GLAXO GROUP LIMITED (GB) | 1989-06-28 | — | — | EP | disclosed |