Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 4/20 | 0.59 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MLNR | O43193 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9510760 | 0.98 | TBXA2R (0.59) | TBXA2RSLC6A3KCNH2ALDH1A1MAPT | |
| SCHEMBL8742924 | 0.90 | TBXA2R (0.73) | TBXA2RSLC6A3KCNH2MEN1MLNR | |
| SCHEMBL8742915 | 0.90 | TBXA2R (0.73) | TBXA2RSLC6A3KCNH2MEN1MLNR | |
| SCHEMBL9506914 | 0.87 | TBXA2R (0.47) | TBXA2RSLC6A3KCNH2 | |
| SCHEMBL27372684 | 0.85 | TBXA2R (0.56) | TBXA2RSLC6A3KCNH2ALDH1A1MAPT | |
| SCHEMBL8742842 | 0.82 | TBXA2R (0.75) | TBXA2RSLC6A3KCNH2MEN1MLNR | |
| SCHEMBL8742836 | 0.82 | TBXA2R (0.75) | TBXA2RSLC6A3KCNH2MEN1MLNR | |
| SCHEMBL9699697 | 0.81 | TBXA2R (0.63) | TBXA2RSLC6A3KCNH2ALDH1A1MAPT | |
| SCHEMBL9507158 | 0.79 | TBXA2R (0.44) | TBXA2RKCNH2 | |
| SCHEMBL9508363 | 0.76 | TBXA2R (0.51) | TBXA2RSLC6A3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0295037-B1 | PHENOL DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1993-08-18 | — | — | EP | disclosed |
| US-5162571-A | Phenol derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-11-10 | — | — | US | disclosed |
| EP-0295037-A2 | Phenol derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1988-12-14 | — | — | EP | disclosed |