Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 4/20 | 0.57 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.51 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | RAD52 | P43351 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9776708 | 0.99 | SLC2A1 (0.60) | SLC2A1NPY5RPTPN11NPC1RAB9A | |
| SCHEMBL9511891 | 0.92 | SLC2A1 (0.50) | SLC2A1PTPN11 | |
| Hydrochloric Acid SCHEMBL9776765 | 0.88 | SLC2A1 (0.66) | SLC2A1NPY5RNPC1RAB9ALMNA | |
| SCHEMBL9776766 | 0.86 | PTPN11 (0.50) | SLC2A1PTPN11LMNASMN1; SMN2RAD52 | |
| SCHEMBL9508868 | 0.82 | SLC2A1 (0.60) | SLC2A1NPC1RAB9ALMNAPKM | |
| SCHEMBL9508214 | 0.81 | — | — | |
| SCHEMBL9776700 | 0.81 | SLC2A1 (0.83) | SLC2A1NPY5RNPC1RAB9ALMNA | |
| Bromide SCHEMBL9508822 | 0.81 | SLC2A1 (0.59) | SLC2A1NPC1RAB9ALMNAPKM | |
| Hydrochloric Acid SCHEMBL9776711 | 0.80 | CSF1R (0.57) | — | |
| Hydrochloric Acid SCHEMBL9776677 | 0.79 | SLC2A1 (0.86) | SLC2A1NPY5RNPC1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0404322-B1 | QUINAZOLINE DERIVATIVES | SMITHKLINE BEECHAM INTERCREDIT B.V. (NL) | 1993-09-22 | — | — | EP | disclosed |
| US-5064833-A | Substituted quinazoline derivatives for use in gastrointestinal diseases | SMITHKLINE BEECHAM INTERCREDIT B.V. (GB) | 1991-11-12 | — | — | US | disclosed |
| EP-0404322-A1 | Quinazoline derivatives | SMITHKLINE BEECHAM INTERCREDIT B.V. (NL) | 1990-12-27 | — | — | EP | disclosed |