Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 4/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 7/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.30 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.30 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.30 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2153928 | 0.97 | — | — | |
| SCHEMBL28889842 | 0.78 | TDP1 (0.50) | CYP3A4TDP1ESR1ESR2TSHR | |
| SCHEMBL18434882 | 0.75 | — | — | |
| SCHEMBL9765929 | 0.75 | ESR1 (0.64) | CYP3A4TDP1ESR1ESR2TSHR | |
| SCHEMBL8052335 | 0.73 | — | — | |
| SCHEMBL40441 | 0.73 | ESR1 (0.70) | CYP3A4TDP1ESR1ESR2TSHR | |
| SCHEMBL11648324 | 0.73 | ESR1 (0.70) | CYP3A4TDP1ESR1ESR2TSHR | |
| SCHEMBL34204 | 0.73 | — | — | |
| SCHEMBL11664569 | 0.73 | TDP1 (0.53) | CYP3A4TDP1ESR1ESR2TSHR | |
| SCHEMBL230096 | 0.73 | TDP1 (0.53) | CYP3A4TDP1ESR1ESR2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0479860-B1 | ORGANIC COMPOUNDS OF PHOSPHORUS COMPLEXED BY BORON | SOCIETE NATIONALE ELF AQUITAINE (FR) | 1993-09-01 | — | — | EP | disclosed |
| EP-0479860-A1 | ORGANIC COMPOUNDS OF PHOSPHORUS COMPLEXED BY BORON. | ELF AQUITAINE (FR) | 1992-04-15 | — | — | EP | disclosed |
| US-5043465-A | Organic phosphorus compounds complexed to boron, their preparation and applications | SOCIETE NATIONALE ELF AQUITAINE (FR) | 1991-08-27 | — | — | US | disclosed |
| WO-1991000286-A1 | ORGANIC COMPOUNDS OF PHOSPHORUS COMPLEXED BY BORON | SOCIETE NATIONALE ELF AQUITAINE (FR) | 1991-01-10 | — | — | WO | disclosed |