Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HHAT | Q5VTY9 | 3/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.53 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.53 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.53 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.53 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.53 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.53 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.53 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.53 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.53 |
| ▸ | KCND3 | Q9UK17 | 1/20 | 0.53 |
| ▸ | PRCP | P42785 | 2/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.51 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9509161 | 0.89 | HHAT (0.61) | HHATCYP2D6CHRM3CHRM2CHRM1 | |
| SCHEMBL29924098 | 0.84 | HHAT (0.57) | HHATCYP2D6CHRM3CHRM2CHRM1 | |
| SCHEMBL1567224 | 0.84 | HHAT (0.57) | HHATCYP2D6CHRM3CHRM2CHRM1 | |
| SCHEMBL1567218 | 0.84 | HHAT (0.57) | HHATCYP2D6CHRM3CHRM2CHRM1 | |
| SCHEMBL12153444 | 0.84 | HHAT (0.57) | HHATCYP2D6CHRM3CHRM2CHRM1 | |
| SCHEMBL12226990 | 0.84 | HHAT (0.60) | HHATCYP2D6CHRM3CHRM2CHRM1 | |
| SCHEMBL1122195 | 0.84 | HHAT (0.60) | HHATCYP2D6CHRM3CHRM2CHRM1 | |
| SCHEMBL698295 | 0.84 | HHAT (0.60) | HHATCYP2D6CHRM3CHRM2CHRM1 | |
| SCHEMBL15598479 | 0.84 | TRPV1 (0.63) | HHATCYP2D6CHRM3CHRM2CHRM1 | |
| SCHEMBL4250247 | 0.84 | HHAT (0.60) | HHATCYP2D6CHRM3CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0230871-B1 | HALOACYL 1-SUBSTITUTED-1,2,3,4-TETRAHYDROISOQUINOLINES AS HERBICIDE ANTIDOTES | Monsanto Company (US) | 1993-09-22 | — | — | EP | claimed |
| EP-0230871-A2 | Haloacyl 1-substituted-1,2,3,4-tetrahydroisoquinolines as herbicide antidotes | Monsanto Company (US) | 1987-08-05 | — | — | EP | claimed |
| EP-0230871-B1 | HALOACYL 1-SUBSTITUTED-1,2,3,4-TETRAHYDROISOQUINOLINES AS HERBICIDE ANTIDOTES | Monsanto Company (US) | 1993-09-22 | — | — | EP | disclosed |
| US-4755218-A | Reducing acetochlor injury to corn by applying with antidote | MONSANTO COMPANY (US) | 1988-07-05 | — | — | US | disclosed |
| EP-0230871-A2 | Haloacyl 1-substituted-1,2,3,4-tetrahydroisoquinolines as herbicide antidotes | Monsanto Company (US) | 1987-08-05 | — | — | EP | disclosed |