Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 9/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.36 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9509369 | 0.96 | TSHR (0.43) | ACACBTSHRHSD17B10SMN1; SMN2GLA | |
| SCHEMBL9512435 | 0.96 | ACACB (0.41) | ACACBTSHRHSD17B10 | |
| SCHEMBL9512321 | 0.96 | TSHR (0.40) | ACACBTSHRHSD17B10SMN1; SMN2MEN1 | |
| SCHEMBL9512346 | 0.95 | HSD17B10 (0.45) | ACACBTSHRHSD17B10SMN1; SMN2MEN1 | |
| SCHEMBL9512409 | 0.95 | HSD17B10 (0.45) | ACACBTSHRHSD17B10SMN1; SMN2MEN1 | |
| SCHEMBL9512279 | 0.95 | HSD17B10 (0.42) | ACACBTSHRHSD17B10SMN1; SMN2MEN1 | |
| SCHEMBL9510175 | 0.95 | ACACB (0.39) | ACACBTSHRHSD17B10SMN1; SMN2GLA | |
| SCHEMBL9510193 | 0.94 | TSHR (0.41) | ACACBTSHRHSD17B10MAPTRAB9A | |
| SCHEMBL9511483 | 0.94 | TSHR (0.44) | ACACBTSHRHSD17B10SMN1; SMN2MEN1 | |
| SCHEMBL9512408 | 0.94 | HSD17B10 (0.47) | ACACBTSHRHSD17B10SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0308438-B1 | LIQUID CRYSTAL PHASE CONTAINING TOLANES | MERCK PATENT GmbH (DE) | 1993-09-29 | — | — | EP | disclosed |