Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 6/20 | 0.45 |
| ▸ | PPARD | Q03181 | 5/20 | 0.45 |
| ▸ | PPARA | Q07869 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | F7 | P08709 | 4/20 | 0.45 |
| ▸ | F3 | P13726 | 4/20 | 0.45 |
| ▸ | FABP4 | P15090 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.45 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.45 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | FABP3 | P05413 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9504795 | 1.00 | PPARG (0.45) | PPARGPPARDPPARAALDH1A1F7 | |
| SCHEMBL9508849 | 1.00 | PPARG (0.45) | PPARGPPARDPPARAALDH1A1F7 | |
| SCHEMBL11020950 | 1.00 | PPARG (0.45) | PPARGPPARDPPARAALDH1A1F7 | |
| SCHEMBL9504667 | 0.97 | EPHX2 (0.47) | PPARGPPARDPPARAALDH1A1F7 | |
| SCHEMBL9504674 | 0.97 | EPHX2 (0.47) | PPARGPPARDPPARAALDH1A1F7 | |
| SCHEMBL9506990 | 0.96 | PPARG (0.46) | PPARGPPARDPPARAALDH1A1F7 | |
| SCHEMBL9506987 | 0.96 | PPARG (0.46) | PPARGPPARDPPARAALDH1A1F7 | |
| SCHEMBL9508227 | 0.89 | PPARG (0.43) | PPARGPPARDPPARAALDH1A1F7 | |
| SCHEMBL9508230 | 0.89 | PPARG (0.43) | PPARGPPARDPPARAALDH1A1F7 | |
| SCHEMBL11023802 | 0.86 | PPARG (0.41) | PPARGPPARDPPARAALDH1A1F7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0161939-B1 | ARYLHYDROXAMATES | E.R. Squibb & Sons, Inc. (US) | 1993-07-21 | — | — | EP | disclosed |
| US-4607053-A | L2POXYGENASE INHIBITORS | E. R. SQUIBB & SONS, INC. (US) | 1986-08-19 | — | — | US | disclosed |
| EP-0161939-A2 | Arylhydroxamates | E.R. Squibb & Sons, Inc. (US) | 1985-11-21 | — | — | EP | disclosed |