SCHEMBL9508885

SCHEMBL9508885

COc1cccc2c(Nc3ccccc3C)nc(Nc3ccccc3C)nc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SLC2A1 P11166 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9776703 0.99 SLC2A1 (0.56) SLC2A1
SCHEMBL9776719 0.92
SCHEMBL9510869 0.92
Hydrochloric Acid SCHEMBL9776804 0.91
SCHEMBL10480698 0.88 SLC2A1 (0.59) SLC2A1
SCHEMBL9776704 0.87 SLC2A1 (0.55) SLC2A1
Hydrochloric Acid SCHEMBL9776747 0.86 SLC2A1 (0.54) SLC2A1
SCHEMBL9776669 0.86
SCHEMBL9776699 0.86
Hydrochloric Acid SCHEMBL3118577 0.85

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5064833-A Substituted quinazoline derivatives for use in gastrointestinal diseases SMITHKLINE BEECHAM INTERCREDIT B.V. (GB) 1991-11-12 US claimed
EP-0322133-B1 QUINAZOLINE DERIVATIVES SmithKline Beecham Intercredit B.V. (NL) 1991-05-22 EP claimed
EP-0404322-B1 QUINAZOLINE DERIVATIVES SMITHKLINE BEECHAM INTERCREDIT B.V. (NL) 1993-09-22 EP disclosed
US-5064833-A Substituted quinazoline derivatives for use in gastrointestinal diseases SMITHKLINE BEECHAM INTERCREDIT B.V. (GB) 1991-11-12 US disclosed
EP-0322133-B1 QUINAZOLINE DERIVATIVES SmithKline Beecham Intercredit B.V. (NL) 1991-05-22 EP disclosed
EP-0404322-A1 Quinazoline derivatives SMITHKLINE BEECHAM INTERCREDIT B.V. (NL) 1990-12-27 EP disclosed
EP-0322133-A1 Quinazoline derivatives SmithKline Beecham Intercredit B.V. (NL) 1989-06-28 EP disclosed
WO-1989005297-A1 COMPOUNDS SMITHKLINE BECKMAN INTERCREDIT B.V. (NL) 1989-06-15 WO disclosed