SCHEMBL9508963

SCHEMBL9508963

C=CC(CC(=O)[C@H](CC(=O)OC1CCCCC1)NC(=O)OC(C)(C)C)C(C)C

nearest known ligand 0.52

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CACNA1B Q00975 6/20 0.52
HDAC4 P56524 2/20 0.41
HDAC1 Q13547 2/20 0.41
HDAC6 Q9UBN7 1/20 0.41
CTSK P43235 3/20 0.40
CTSS P25774 2/20 0.40
CYP2D6 P10635 1/20 0.37
CASP1 P29466 1/20 0.37
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA7 P43166 1/20 0.34
KMT2A Q03164 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
TSHR P16473 1/20 0.34
ITGB3 P05106 1/20 0.33
ITGA2B P08514 1/20 0.33
EPHX1 P07099 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9507121 0.90 CACNA1B (0.53) CACNA1BHDAC4HDAC1HDAC6CTSK
SCHEMBL9504947 0.84 CACNA1B (0.53) CACNA1BHDAC4HDAC1HDAC6CTSK
SCHEMBL7109105 0.81 CACNA1B (0.61) CACNA1BHDAC4HDAC1HDAC6CTSK
SCHEMBL29400846 0.81 CACNA1B (0.61) CACNA1BHDAC4HDAC1HDAC6CTSK
SCHEMBL14017648 0.81 CACNA1B (0.61) CACNA1BHDAC4HDAC1HDAC6CTSK
SCHEMBL5351823 0.81 CACNA1B (0.67) CACNA1BHDAC4HDAC1HDAC6CTSK
SCHEMBL18460226 0.81 CACNA1B (0.61) CACNA1BHDAC4HDAC1HDAC6CTSK
SCHEMBL5354120 0.79 CACNA1B (0.69) CACNA1BHDAC4HDAC1HDAC6CTSK
SCHEMBL5354817 0.79 CACNA1B (0.61) CACNA1BHDAC4HDAC1HDAC6CTSK
SCHEMBL5345653 0.77 CACNA1B (0.55) CACNA1BHDAC4HDAC1HDAC6CTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0556405-A1 PSEUDOPENTAPEPTIDES WITH IMMUNOMODULATING ACTIVITY Japan Tobacco Inc. (JP) 1993-08-25 EP disclosed
WO-1993004080-A1 PSEUDOPENTAPEPTIDES WITH IMMUNOMODULATING ACTIVITY JAPAN TOBACCO INC. (JP) 1993-03-04 WO disclosed