SCHEMBL9508991

SCHEMBL9508991

COCc1cc2c(cc1Cl)Sc1cc(Cl)ccc1S2

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOX1 Q9Y5S8 2/20 0.39
HTT P42858 1/20 0.39
IDO1 P14902 3/20 0.39
BCHE P06276 2/20 0.36
ACHE P22303 2/20 0.36
S1PR4 O95977 1/20 0.35
ALDH1A1 P00352 1/20 0.34
CYP3A4 P08684 4/20 0.33
CYP1A2 P05177 3/20 0.33
CYP2C19 P33261 3/20 0.33
MAPK1 P28482 2/20 0.33
CYP2C9 P11712 1/20 0.33
LMNA P02545 3/20 0.33
TDP1 Q9NUW8 2/20 0.33
CYP2D6 P10635 2/20 0.33
SLC22A1 O15245 1/20 0.33
MLNR O43193 1/20 0.33
NR1I2 O75469 1/20 0.33
ABCB11 O95342 1/20 0.33
CHRM2 P08172 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1989192 0.75 IDO1 (0.64) HTTIDO1S1PR4ALDH1A1CYP3A4
SCHEMBL1145754 0.75 IDO1 (0.44) HTTIDO1S1PR4ALDH1A1CYP3A4
SCHEMBL9698848 0.75 NOX1 (0.42) NOX1BCHEACHEALDH1A1TP53
SCHEMBL9698315 0.75 PRKCE (0.31) ALDH1A1TDP1MEN1KMT2A
SCHEMBL9508955 0.74 BCHE (0.48) NOX1IDO1BCHEACHEALDH1A1
SCHEMBL9511257 0.74 BCHE (0.48) NOX1IDO1BCHEACHEALDH1A1
SCHEMBL4929830 0.74
SCHEMBL25085954 0.72 PRKCE (0.41) HTTIDO1S1PR4ALDH1A1LMNA
SCHEMBL3221093 0.69 IDO1 (0.56) HTTIDO1S1PR4ALDH1A1CYP3A4
SCHEMBL29018344 0.69 IDO1 (0.45) HTTIDO1S1PR4ALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0399293-B1 PROCESS FOR PREPARING 2-CHLORO-4-NITRO-ALKYLBENZENE BAYER AG (DE) 1993-09-01 EP disclosed
EP-0399293-A1 Process for preparing 2-chloro-4-nitro-alkylbenzene BAYER AG (DE) 1990-11-28 EP disclosed