Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 8/20 | 0.37 |
| ▸ | ESR1 | P03372 | 6/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | XDH | P47989 | 1/20 | 0.32 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10423236 | 1.00 | ESR2 (0.37) | ESR2ESR1CYP3A4CYP2C9ALDH1A1 | |
| SCHEMBL9297464 | 1.00 | ESR2 (0.37) | ESR2ESR1CYP3A4CYP2C9ALDH1A1 | |
| SCHEMBL9297253 | 0.95 | ESR2 (0.40) | ESR2ESR1CYP3A4CYP2C9ALDH1A1 | |
| SCHEMBL11014791 | 0.95 | ESR2 (0.40) | ESR2ESR1CYP3A4CYP2C9ALDH1A1 | |
| SCHEMBL10935693 | 0.90 | ESR2 (0.43) | ESR2ESR1CYP3A4CYP2C9ALDH1A1 | |
| SCHEMBL10904852 | 0.90 | ESR2 (0.43) | ESR2ESR1CYP3A4CYP2C9ALDH1A1 | |
| SCHEMBL10935701 | 0.90 | ESR2 (0.43) | ESR2ESR1CYP3A4CYP2C9ALDH1A1 | |
| SCHEMBL10935713 | 0.90 | ESR2 (0.43) | ESR2ESR1CYP3A4CYP2C9ALDH1A1 | |
| SCHEMBL10904861 | 0.90 | ESR2 (0.43) | ESR2ESR1CYP3A4CYP2C9ALDH1A1 | |
| SCHEMBL10904854 | 0.90 | ESR2 (0.43) | ESR2ESR1CYP3A4CYP2C9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0318003-B1 | A liquid crystal composition for twist nematic mode | CHISSO CORP (JP) | 1993-10-20 | — | — | EP | disclosed |
| US-4923632-A | LOW THRESHOLD-VOLTAGE AND TEMPERATURE DEPENDENCY; CYCLOHEXYL-AND FLUORO-SUBSTITUTED BENZENE | CHISSO CORPORATION (JP) | 1990-05-08 | — | — | US | disclosed |
| US-4477369-A | New high temperature liquid-crystalline substances consisting of 4 or 5 six-member-rings and liquid-crystalline compositions containing same | CHISSO CORPORATION (JP) | 1984-10-16 | — | — | US | disclosed |