Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MGAM | O43451 | 1/20 | 0.46 |
| ▸ | SI | P14410 | 1/20 | 0.46 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7866061 | 0.89 | TSHR (0.50) | TSHRALDH1A1HTTLMNACYP1A2 | |
| SCHEMBL111821 | 0.89 | GAA (0.52) | TSHRALDH1A1HTTLMNACYP1A2 | |
| SCHEMBL20841661 | 0.89 | MGAM (0.52) | TSHRALDH1A1HTTLMNACYP1A2 | |
| SCHEMBL14643394 | 0.88 | CYP1A2 (0.53) | TSHRALDH1A1HTTLMNACYP1A2 | |
| SCHEMBL18736929 | 0.88 | TSHR (0.49) | TSHRALDH1A1HTTLMNACYP1A2 | |
| SCHEMBL8503864 | 0.88 | TSHR (0.49) | TSHRALDH1A1HTTLMNACYP1A2 | |
| SCHEMBL14595040 | 0.88 | TSHR (0.44) | TSHRALDH1A1HTTLMNACYP1A2 | |
| SCHEMBL7527314 | 0.86 | MGAM (0.50) | TSHRALDH1A1HTTLMNACYP1A2 | |
| SCHEMBL14627439 | 0.86 | TSHR (0.43) | TSHRALDH1A1HTTLMNACYP1A2 | |
| SCHEMBL22710170 | 0.84 | GAA (0.48) | TSHRALDH1A1HTTLMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0344983-B1 | PROCESS FOR PREPARING 2- AND 4-ALKOXYCARBONYL THIOLAN-3-ONES | JOHN WYETH & BROTHER LIMITED (GB) | 1993-09-15 | — | — | EP | disclosed |
| EP-0344983-A1 | Process for preparing 2- and 4-alkoxycarbonyl thiolan-3-ones | JOHN WYETH & BROTHER LIMITED (GB) | 1989-12-06 | — | — | EP | disclosed |