Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 8/20 | 0.36 |
| ▸ | ACACB | O00763 | 5/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | MPL | P40238 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | RARB | P10826 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | FPR1 | P21462 | 1/20 | 0.32 |
| ▸ | FPR3 | P25089 | 1/20 | 0.32 |
| ▸ | GPR183 | P32249 | 1/20 | 0.32 |
| ▸ | APLNR | P35414 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | GPR65 | Q8IYL9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9512399 | 1.00 | FFAR1 (0.36) | FFAR1ACACBCYP2A6MPLTSHR | |
| SCHEMBL9508906 | 0.96 | FFAR1 (0.39) | FFAR1ACACBMPLTSHRHSD17B10 | |
| SCHEMBL9511355 | 0.93 | CYP2A6 (0.39) | FFAR1ACACBCYP2A6RARBFFAR4 | |
| SCHEMBL9511464 | 0.92 | TSHR (0.40) | FFAR1MPLTSHRHSD17B10RARB | |
| SCHEMBL9510180 | 0.92 | TSHR (0.40) | FFAR1MPLTSHRHSD17B10RARB | |
| SCHEMBL9512281 | 0.92 | FFAR1 (0.42) | FFAR1ACACBMPLTSHRHSD17B10 | |
| SCHEMBL9512306 | 0.91 | HSD17B10 (0.46) | MPLTSHRHSD17B10RARBCHRM2 | |
| SCHEMBL9508830 | 0.91 | HSD17B10 (0.46) | MPLTSHRHSD17B10RARBCHRM2 | |
| SCHEMBL9510034 | 0.90 | TSHR (0.41) | FFAR1ACACBMPLTSHRHSD17B10 | |
| SCHEMBL9508790 | 0.90 | TSHR (0.41) | FFAR1ACACBMPLTSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0308438-B1 | LIQUID CRYSTAL PHASE CONTAINING TOLANES | MERCK PATENT GmbH (DE) | 1993-09-29 | — | — | EP | disclosed |