SCHEMBL9509324

SCHEMBL9509324

CCCCc1ccc(CCc2ccc(C#Cc3ccc(C)cc3)cc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 4/20 0.54
HSD17B10 Q99714 3/20 0.46
TSHR P16473 1/20 0.46
CA2 P00918 2/20 0.44
CA1 P00915 1/20 0.44
KCNH2 Q12809 4/20 0.44
CNR2 P34972 1/20 0.43
ALDH1A1 P00352 2/20 0.43
HPGD P15428 1/20 0.43
CYP1A2 P05177 1/20 0.42
CYP2A6 P11509 1/20 0.42
TAAR1 Q96RJ0 1/20 0.42
FFAR4 Q5NUL3 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
SKP2 Q13309 1/20 0.42
IGF1R P08069 1/20 0.42
ALOX15 P16050 1/20 0.42
ESR1 P03372 2/20 0.41
ADRA2A P08913 2/20 0.41
ADORA3 P0DMS8 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9328412 0.98 FFAR1 (0.56) FFAR1HSD17B10TSHRCA2CA1
SCHEMBL9346602 0.98 FFAR1 (0.56) FFAR1HSD17B10TSHRCA2CA1
SCHEMBL9508942 0.94 HSD17B10 (0.53) FFAR1HSD17B10TSHRCA2KCNH2
SCHEMBL9346191 0.92 HSD17B10 (0.54) FFAR1HSD17B10TSHRCA2KCNH2
SCHEMBL9330346 0.92 HSD17B10 (0.54) FFAR1HSD17B10TSHRCA2KCNH2
SCHEMBL9508729 0.92 HSD17B10 (0.52) FFAR1HSD17B10TSHRCA2CA1
SCHEMBL9328421 0.91 HSD17B10 (0.57) FFAR1HSD17B10TSHRKCNH2ALDH1A1
SCHEMBL7511631 0.91 HSD17B10 (0.57) FFAR1HSD17B10TSHRKCNH2ALDH1A1
SCHEMBL9327028 0.91 HSD17B10 (0.57) FFAR1HSD17B10TSHRKCNH2ALDH1A1
SCHEMBL9328451 0.91 HSD17B10 (0.57) FFAR1HSD17B10TSHRKCNH2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0308438-B1 LIQUID CRYSTAL PHASE CONTAINING TOLANES MERCK PATENT GmbH (DE) 1993-09-29 EP disclosed