Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.40 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.38 |
| ▸ | TACR2 | P21452 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10516393 | 1.00 | HSD17B10 (0.45) | HSD17B10TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL9508818 | 1.00 | HSD17B10 (0.45) | HSD17B10TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL9512378 | 1.00 | HSD17B10 (0.45) | HSD17B10TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL9512366 | 1.00 | HSD17B10 (0.45) | HSD17B10TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL9512402 | 1.00 | HSD17B10 (0.45) | HSD17B10TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL9512252 | 0.99 | HSD17B10 (0.43) | HSD17B10TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL9511463 | 0.98 | HSD17B10 (0.49) | HSD17B10TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL9510198 | 0.98 | HSD17B10 (0.49) | HSD17B10TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL9512346 | 0.97 | HSD17B10 (0.45) | HSD17B10TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL9512279 | 0.97 | HSD17B10 (0.42) | HSD17B10TSHRALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0308438-B1 | LIQUID CRYSTAL PHASE CONTAINING TOLANES | MERCK PATENT GmbH (DE) | 1993-09-29 | — | — | EP | disclosed |
| EP-0308438-A1 | Liquid crystal phase containing tolanes. | MERCK PATENT GMBH (DE) | 1989-03-29 | — | — | EP | disclosed |
| WO-1988007514-A1 | TOLANES | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1988-10-06 | — | — | WO | disclosed |