Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 9/20 | 0.48 |
| ▸ | MPL | P40238 | 3/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | RARA | P10276 | 2/20 | 0.42 |
| ▸ | RARG | P13631 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.41 |
| ▸ | TACR2 | P21452 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SHBG | P04278 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9486831 | 0.97 | RARB (0.51) | RARBHSD11B1HSD17B10TSHRRARA | |
| SCHEMBL9497760 | 0.97 | RARB (0.48) | RARBMPLHSD11B1HSD17B10TSHR | |
| SCHEMBL9485948 | 0.97 | RARB (0.48) | RARBMPLHSD11B1HSD17B10TSHR | |
| SCHEMBL9485510 | 0.97 | RARB (0.51) | RARBHSD11B1HSD17B10TSHRRARA | |
| SCHEMBL9486894 | 0.97 | RARB (0.51) | RARBHSD11B1HSD17B10TSHRRARA | |
| SCHEMBL9563854 | 0.97 | RARB (0.50) | RARBMPLHSD11B1HSD17B10TSHR | |
| SCHEMBL9494649 | 0.95 | RARB (0.50) | RARBMPLHSD17B10TSHRRARA | |
| SCHEMBL9493114 | 0.95 | RARB (0.50) | RARBMPLHSD17B10TSHRRARA | |
| SCHEMBL9487333 | 0.95 | RARB (0.49) | RARBMPLHSD11B1HSD17B10TSHR | |
| SCHEMBL9494664 | 0.95 | RARB (0.49) | RARBMPLHSD11B1HSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0362318-B1 | 2,3-DIFLUOROBIPHENYLS | MERCK PATENT GmbH (DE) | 1993-08-04 | — | — | EP | disclosed |