Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | PREP | P48147 | 2/20 | 0.33 |
| ▸ | PHGDH | O43175 | 1/20 | 0.32 |
| ▸ | ACE | P12821 | 2/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11743297 | 0.81 | MEN1 (0.50) | MEN1KMT2APSEN1PSEN2APH1B | |
| SCHEMBL11618812 | 0.78 | MEN1 (0.46) | MEN1KMT2APSEN1PSEN2APH1B | |
| SCHEMBL11750954 | 0.75 | KMT2A (0.48) | MEN1KMT2APSEN1PSEN2APH1B | |
| SCHEMBL11750199 | 0.74 | MEN1 (0.45) | MEN1KMT2APSEN1PSEN2APH1B | |
| SCHEMBL11750968 | 0.72 | MEN1 (0.44) | MEN1KMT2APSEN1PSEN2APH1B | |
| SCHEMBL14592916 | 0.71 | MEN1 (0.39) | MEN1KMT2ADPP4PREPACE | |
| SCHEMBL11750206 | 0.71 | MEN1 (0.42) | MEN1KMT2APSEN1PSEN2APH1B | |
| SCHEMBL11749105 | 0.71 | KMT2A (0.45) | MEN1KMT2APSEN1PSEN2APH1B | |
| SCHEMBL11282748 | 0.70 | DPP7 (0.46) | DPP4PREPHSD11B1DPP7 | |
| SCHEMBL11747201 | 0.69 | KMT2A (0.43) | MEN1KMT2APSEN1PSEN2APH1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0230871-B1 | HALOACYL 1-SUBSTITUTED-1,2,3,4-TETRAHYDROISOQUINOLINES AS HERBICIDE ANTIDOTES | Monsanto Company (US) | 1993-09-22 | — | — | EP | disclosed |
| US-4846880-A | 2-(Dichloroacetyl)-3-substituted-1,2,3,4-tetrahydroisoquinolines as herbicide antidotes | MONSANTO COMPANY (US) | 1989-07-11 | — | — | US | disclosed |
| US-4755218-A | Reducing acetochlor injury to corn by applying with antidote | MONSANTO COMPANY (US) | 1988-07-05 | — | — | US | disclosed |
| EP-0230871-A2 | Haloacyl 1-substituted-1,2,3,4-tetrahydroisoquinolines as herbicide antidotes | Monsanto Company (US) | 1987-08-05 | — | — | EP | disclosed |