Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | RARB | P10826 | 7/20 | 0.39 |
| ▸ | RARA | P10276 | 2/20 | 0.39 |
| ▸ | RARG | P13631 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9508748 | 0.99 | HSD17B10 (0.50) | TSHRHSD17B10FFAR1RARBRARA | |
| SCHEMBL9510181 | 0.99 | HSD17B10 (0.50) | TSHRHSD17B10FFAR1RARBRARA | |
| SCHEMBL9510153 | 0.97 | HSD17B10 (0.43) | TSHRHSD17B10FFAR1RARBRARA | |
| SCHEMBL9512554 | 0.96 | HSD17B10 (0.46) | TSHRHSD17B10FFAR1RARBRARA | |
| SCHEMBL9508776 | 0.96 | HSD17B10 (0.46) | TSHRHSD17B10FFAR1RARBRARA | |
| SCHEMBL9510224 | 0.96 | TSHR (0.43) | TSHRHSD17B10FFAR1RARBRARA | |
| SCHEMBL9509124 | 0.94 | FFAR1 (0.42) | TSHRHSD17B10FFAR1 | |
| SCHEMBL9511390 | 0.91 | FFAR1 (0.42) | TSHRHSD17B10FFAR1 | |
| SCHEMBL9509905 | 0.90 | HSD17B10 (0.48) | TSHRHSD17B10RARBRARARARG | |
| SCHEMBL9512408 | 0.89 | HSD17B10 (0.47) | TSHRHSD17B10RARBRARARARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0308438-B1 | LIQUID CRYSTAL PHASE CONTAINING TOLANES | MERCK PATENT GmbH (DE) | 1993-09-29 | — | — | EP | disclosed |