Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | BLM | P54132 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.46 |
| ▸ | BTK | Q06187 | 1/20 | 0.38 |
| ▸ | ARG1 | P05089 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5746785 | 1.00 | MEN1 (0.61) | MEN1BLMKMT2ASLC1A2BTK | |
| SCHEMBL27190337 | 1.00 | MEN1 (0.61) | MEN1BLMKMT2ASLC1A2BTK | |
| SCHEMBL2177343 | 0.87 | MEN1 (0.61) | MEN1BLMKMT2ASLC1A2BTK | |
| SCHEMBL17756096 | 0.87 | MEN1 (0.61) | MEN1BLMKMT2ASLC1A2BTK | |
| SCHEMBL11931404 | 0.86 | MEN1 (0.42) | MEN1BLMKMT2ABTKRECQL | |
| SCHEMBL28060859 | 0.81 | MEN1 (0.67) | MEN1BLMKMT2ASLC1A2ARG1 | |
| SCHEMBL7619070 | 0.77 | SLC1A2 (0.42) | MEN1BLMKMT2ASLC1A2BTK | |
| SCHEMBL17756064 | 0.77 | SLC1A2 (0.58) | MEN1BLMKMT2ASLC1A2BTK | |
| SCHEMBL3427826 | 0.77 | SLC1A2 (0.58) | MEN1BLMKMT2ASLC1A2BTK | |
| SCHEMBL730491 | 0.77 | MEN1 (1.00) | MEN1BLMKMT2ASLC1A2ARG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118043316-A | Factor XIIa inhibitors | 卢纳克治疗有限公司 | 2024-05-14 | — | — | CN | disclosed |
| EP-4347578-A1 | FACTOR XIIA INHIBITORS | Lunac Therpeutics Ltd (GB) | 2024-04-10 | — | — | EP | disclosed |
| WO-2022248883-A1 | FACTOR XIIA INHIBITORS | LUNAC THERAPEUTICS LTD (GB) | 2022-12-01 | — | — | WO | disclosed |
| EP-0557375-A1 | NEW HETEROCYCLIC COMPOUNDS AS ANTAGONISTS OF EXCITATORY AMINO ACID RECEPTORS, PROCESSES FOR THEIR PREPARATION AND THEIR USE | Astra Aktiebolag (SE) | 1993-09-01 | — | — | EP | disclosed |
| WO-1992008724-A1 | NEW HETEROCYCLIC COMPOUNDS AS ANTAGONISTS OF EXCITATORY AMINO ACID RECEPTORS, PROCESSES FOR THEIR PREPARATION AND THEIR USE | AKTIEBOLAGET ASTRA (SE) | 1992-05-29 | — | — | WO | disclosed |