Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | KIF11 | P52732 | 7/20 | 0.40 |
| ▸ | LTA4H | P09960 | 3/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9513189 | 1.00 | CYP3A4 (0.56) | CYP3A4CYP1A2RECQLMAPK1KIF11 | |
| Fumaric Acid SCHEMBL9167241 | 0.94 | CYP3A4 (0.51) | CYP3A4CYP1A2RECQLMAPK1KIF11 | |
| Fumaric Acid SCHEMBL9172396 | 0.94 | CYP3A4 (0.51) | CYP3A4CYP1A2RECQLMAPK1KIF11 | |
| Maleic Acid SCHEMBL9167223 | 0.94 | CYP3A4 (0.51) | CYP3A4CYP1A2RECQLMAPK1KIF11 | |
| Maleic Acid SCHEMBL9172374 | 0.94 | CYP3A4 (0.51) | CYP3A4CYP1A2RECQLMAPK1KIF11 | |
| SCHEMBL9513964 | 0.84 | CYP1A2 (0.62) | CYP3A4CYP1A2RECQLMAPK1KIF11 | |
| SCHEMBL9512544 | 0.84 | CYP1A2 (0.62) | CYP3A4CYP1A2RECQLMAPK1KIF11 | |
| Hydrochloric Acid SCHEMBL9167246 | 0.83 | MAPK1 (0.63) | CYP3A4CYP1A2RECQLMAPK1KIF11 | |
| Hydrochloric Acid SCHEMBL9171169 | 0.83 | MAPK1 (0.63) | CYP3A4CYP1A2RECQLMAPK1KIF11 | |
| SCHEMBL9171380 | 0.81 | CYP3A4 (0.65) | CYP3A4CYP1A2RECQLMAPK1KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0326240-B1 | 2-Amino acetamide derivatives | FISONS CORP (US) | 1993-10-20 | — | — | EP | claimed |