Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | RECQL | P46063 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | TERT | O14746 | 1/20 | 0.41 |
| ▸ | CTRB1 | P17538 | 3/20 | 0.40 |
| ▸ | KIF11 | P52732 | 2/20 | 0.40 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.39 |
| ▸ | F7 | P08709 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9512649 | 0.87 | CYP3A4 (0.65) | CYP1A2CYP3A4RECQLMAPK1CTRB1 | |
| SCHEMBL9171380 | 0.87 | CYP3A4 (0.65) | CYP1A2CYP3A4RECQLMAPK1CTRB1 | |
| SCHEMBL9514532 | 0.87 | CYP3A4 (0.65) | CYP1A2CYP3A4RECQLMAPK1CTRB1 | |
| Hydrochloric Acid SCHEMBL9171943 | 0.85 | MAPK1 (0.66) | CYP1A2CYP3A4RECQLMAPK1CTRB1 | |
| Hydrochloric Acid SCHEMBL9163195 | 0.85 | MAPK1 (0.66) | CYP1A2CYP3A4RECQLMAPK1CTRB1 | |
| SCHEMBL9513149 | 0.83 | CYP1A2 (0.82) | CYP1A2CYP3A4RECQLMAPK1F7 | |
| Hydrochloric Acid SCHEMBL9513957 | 0.82 | MAPK1 (0.82) | CYP1A2CYP3A4RECQLMAPK1F7 | |
| SCHEMBL16884455 | 0.82 | CYP3A4 (0.66) | CYP1A2CYP3A4RECQLMAPK1OPRD1 | |
| SCHEMBL9510622 | 0.81 | CYP1A2 (0.58) | CYP1A2CYP3A4RECQLMAPK1CTRB1 | |
| Hydrochloric Acid SCHEMBL9511071 | 0.81 | MAPK1 (0.67) | CYP1A2CYP3A4RECQLMAPK1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0326240-B1 | 2-Amino acetamide derivatives | FISONS CORP (US) | 1993-10-20 | — | — | EP | claimed |
| EP-0401253-A1 | 2-AMINO ACETAMIDE DERIVATIVES | FISONS CORPORATION (US) | 1990-12-12 | — | — | EP | claimed |
| US-4871872-A | 2-[(2-aminoacetyl)amino]acetamide derivatives | FISONS CORPORATION (US) | 1989-10-03 | — | — | US | claimed |
| EP-0326240-A1 | 2-Amino acetamide derivatives | FISONS CORPORATION (US) | 1989-08-02 | — | — | EP | claimed |
| WO-1989006646-A1 | 2-AMINO ACETAMIDE DERIVATIVES | FISONS CORPORATION (US) | 1989-07-27 | — | — | WO | claimed |
| EP-0326240-B1 | 2-Amino acetamide derivatives | FISONS CORP (US) | 1993-10-20 | — | — | EP | disclosed |
| EP-0401253-A1 | 2-AMINO ACETAMIDE DERIVATIVES | FISONS CORPORATION (US) | 1990-12-12 | — | — | EP | disclosed |
| US-4871872-A | 2-[(2-aminoacetyl)amino]acetamide derivatives | FISONS CORPORATION (US) | 1989-10-03 | — | — | US | disclosed |
| EP-0326240-A1 | 2-Amino acetamide derivatives | FISONS CORPORATION (US) | 1989-08-02 | — | — | EP | disclosed |
| WO-1989006646-A1 | 2-AMINO ACETAMIDE DERIVATIVES | FISONS CORPORATION (US) | 1989-07-27 | — | — | WO | disclosed |