SCHEMBL9511141

SCHEMBL9511141

CCCCCCCC1(c2ccccc2CCCC)C=CC(C(=O)O)C=C1

nearest known ligand 0.43

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYSLTR2 Q9NS75 4/20 0.43
CYSLTR1 Q9Y271 4/20 0.43
BID P55957 3/20 0.39
MCL1 Q07820 3/20 0.39
BCL2L1 Q07817 2/20 0.39
BAK1 Q16611 2/20 0.39
KAT8 Q9H7Z6 2/20 0.39
PPARA Q07869 2/20 0.39
PPARG P37231 1/20 0.39
EP300 Q09472 1/20 0.39
KAT2A Q92830 1/20 0.39
KAT2B Q92831 1/20 0.39
KAT5 Q92993 1/20 0.39
SAE1 Q9UBE0 1/20 0.39
LIPG Q9Y5X9 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5666120 0.99 CYSLTR2 (0.41) CYSLTR2CYSLTR1BIDMCL1BCL2L1
SCHEMBL9247767 0.98 CYSLTR2 (0.45) CYSLTR2CYSLTR1BIDMCL1BCL2L1
SCHEMBL11135660 0.98 CYSLTR2 (0.45) CYSLTR2CYSLTR1BIDMCL1BCL2L1
SCHEMBL9155406 0.98 CYSLTR2 (0.45) CYSLTR2CYSLTR1BIDMCL1BCL2L1
SCHEMBL20594627 0.96 CYSLTR2 (0.43) CYSLTR2CYSLTR1BIDMCL1BCL2L1
SCHEMBL9755589 0.95 CYSLTR2 (0.40) CYSLTR2CYSLTR1BIDMCL1BCL2L1
SCHEMBL5665940 0.95 CYSLTR2 (0.39) CYSLTR2CYSLTR1BIDMCL1BCL2L1
SCHEMBL5665859 0.94 CYSLTR2 (0.43) CYSLTR2CYSLTR1BIDMCL1BCL2L1
SCHEMBL22157658 0.85 CYSLTR2 (0.34) CYSLTR2CYSLTR1
SCHEMBL20594623 0.85 CYSLTR2 (0.34) CYSLTR2CYSLTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0187768-B1 LIQUID CRYSTAL TEMPERATURE SENSOR AND MATERIALS FERGASON JAMES L (US) 1993-11-03 EP disclosed
US-5130828-A Liquid crystal temperature sensor and materials MANCHESTER R&D PARTNERSHIP (US) 1992-07-14 US disclosed
EP-0187768-A4 LIQUID CRYSTAL TEMPERATURE SENSOR AND MATERIALS. FERGASON JAMES L 1989-03-09 EP disclosed
EP-0187768-A1 LIQUID CRYSTAL TEMPERATURE SENSOR AND MATERIALS. FERGASON JAMES L 1986-07-23 EP disclosed
WO-1985005467-A1 LIQUID CRYSTAL TEMPERATURE SENSOR AND MATERIALS FERGASON JAMES L 1985-12-05 WO disclosed
US-4385844-A THERMOSENSITIVE NON-CHLOLESTERIC COMPOUND AND ALKYLBENZOATE LIQUID CRYSTALS BECTON, DICKINSON AND COMPANY (US) 1983-05-31 US disclosed
US-4296631-A AND METHOD OF MODIFYING THE HYSTERETIC BEHAVIOR BECTON, DICKINSON AND COMPANY (US) 1981-10-27 US disclosed
US-4140016-A CHOLESTERIC LIQUID CRYSTAL THERMOMETERS, BENZOIC ESTER DERIVATIVES BECTON, DICKINSON AND COMPANY (US) 1979-02-20 US disclosed