Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.30 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9511261 | 1.00 | MAPT (0.39) | MAPTCYP3A4CYP2C9ALDH1A1USP2 | |
| SCHEMBL9511112 | 0.98 | MAPT (0.37) | MAPTCYP3A4CYP2C9ALDH1A1TDP1 | |
| SCHEMBL9508704 | 0.94 | CYP3A4 (0.35) | MAPTCYP3A4CYP2C9TDP1 | |
| SCHEMBL9511234 | 0.86 | TDP1 (0.33) | MAPTCYP3A4CYP2C9TDP1 | |
| SCHEMBL5376783 | 0.82 | TSHR (0.42) | ALDH1A1TSHR | |
| SCHEMBL15442569 | 0.82 | TSHR (0.42) | ALDH1A1TSHR | |
| SCHEMBL11672964 | 0.82 | TSHR (0.42) | ALDH1A1TSHR | |
| SCHEMBL11670947 | 0.82 | TSHR (0.42) | ALDH1A1TSHR | |
| SCHEMBL5537143 | 0.82 | TSHR (0.40) | MAPTCYP3A4CYP2C9ALDH1A1USP2 | |
| SCHEMBL7638420 | 0.80 | TDP1 (0.33) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0388960-B1 | OPTICALLY ACTIVE COMPOUNDS AND THEIR PREPARATION AND USE | HITACHI, LTD. (JP) | 1993-10-06 | — | — | EP | disclosed |
| US-5152919-A | Stability, chemical resistance, high speed response, large spo ntaneous polarization, molecular orientation and wide temperat ure range | HITACHI, LTD. (JP) | 1992-10-06 | — | — | US | disclosed |
| EP-0388960-A1 | Optically active compounds and their preparation and use | HITACHI, LTD. (JP) | 1990-09-26 | — | — | EP | disclosed |