Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A2 | P43004 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | BLM | P54132 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.38 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.38 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.38 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9131137 | 0.80 | SLC1A2 (0.58) | SLC1A2MEN1KMT2ABLMALDH1A1 | |
| SCHEMBL9131149 | 0.80 | SLC1A2 (0.58) | SLC1A2MEN1KMT2ABLMALDH1A1 | |
| SCHEMBL9131854 | 0.80 | SLC1A2 (0.58) | SLC1A2MEN1KMT2ABLMALDH1A1 | |
| SCHEMBL9131600 | 0.78 | MEN1 (0.61) | SLC1A2MEN1KMT2ABLMALDH1A1 | |
| SCHEMBL9130042 | 0.78 | MEN1 (0.61) | SLC1A2MEN1KMT2ABLMALDH1A1 | |
| SCHEMBL9130500 | 0.78 | MEN1 (0.61) | SLC1A2MEN1KMT2ABLMALDH1A1 | |
| SCHEMBL9130013 | 0.78 | MEN1 (0.61) | SLC1A2MEN1KMT2ABLMALDH1A1 | |
| SCHEMBL9132740 | 0.78 | MEN1 (0.61) | SLC1A2MEN1KMT2ABLMALDH1A1 | |
| SCHEMBL1428518 | 0.78 | MEN1 (0.61) | SLC1A2MEN1KMT2ABLMALDH1A1 | |
| SCHEMBL9132727 | 0.78 | MEN1 (0.61) | SLC1A2MEN1KMT2ABLMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0557375-A1 | NEW HETEROCYCLIC COMPOUNDS AS ANTAGONISTS OF EXCITATORY AMINO ACID RECEPTORS, PROCESSES FOR THEIR PREPARATION AND THEIR USE | Astra Aktiebolag (SE) | 1993-09-01 | — | — | EP | disclosed |
| WO-1992008724-A1 | NEW HETEROCYCLIC COMPOUNDS AS ANTAGONISTS OF EXCITATORY AMINO ACID RECEPTORS, PROCESSES FOR THEIR PREPARATION AND THEIR USE | AKTIEBOLAGET ASTRA (SE) | 1992-05-29 | — | — | WO | disclosed |