Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.33 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.33 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.32 |
| ▸ | DRD3 | P35462 | 2/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ANPEP | P15144 | 1/20 | 0.31 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | LTA4H | P09960 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9511303 | 1.00 | MEN1 (0.39) | MEN1KMT2AMAPTATMCARM1 | |
| SCHEMBL8189073 | 0.98 | MEN1 (0.43) | MEN1KMT2AMAPTATMCARM1 | |
| SCHEMBL8236423 | 0.85 | GAA (0.36) | MAPTSIGMAR1ALDH1A1CYP2D6 | |
| SCHEMBL17788475 | 0.84 | USP2 (0.45) | MEN1KMT2AMAPTALDH1A1ANPEP | |
| SCHEMBL9103896 | 0.82 | MEN1 (0.39) | MEN1KMT2AMAPTATMCARM1 | |
| SCHEMBL9103884 | 0.82 | MEN1 (0.39) | MEN1KMT2AMAPTATMCARM1 | |
| SCHEMBL13808507 | 0.82 | CYP3A4 (0.36) | MEN1KMT2AHRH3ALDH1A1LMNA | |
| SCHEMBL13817508 | 0.80 | MEN1 (0.43) | MEN1KMT2AMAPTATMCARM1 | |
| Hydrochloric Acid SCHEMBL9105755 | 0.80 | KMT2A (0.38) | MEN1KMT2AMAPTATMCARM1 | |
| Hydrochloric Acid SCHEMBL9105769 | 0.80 | KMT2A (0.38) | MEN1KMT2AMAPTATMCARM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0254545-B1 | DIAMINE COMPOUNDS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-10-06 | — | — | EP | disclosed |
| EP-0254545-A2 | Diamine compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-01-27 | — | — | EP | disclosed |