Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | NR2E3 | Q9Y5X4 | 2/20 | 0.39 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.37 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10848706 | 0.82 | TSHR (0.40) | TSHRTDP1EPHX2SIRT2MAPT | |
| SCHEMBL22754195 | 0.81 | TSHR (0.43) | TSHRTDP1EPHX2SIRT2MAPT | |
| SCHEMBL8829497 | 0.80 | NPC1 (0.48) | TSHRTDP1EPHX2PPARGNR2E3 | |
| SCHEMBL9509126 | 0.76 | BRD4 (0.44) | TSHREPHX2L3MBTL1GAAKMT2A | |
| SCHEMBL4942582 | 0.76 | TSHR (0.58) | TSHRTDP1EPHX2GLAMAPT | |
| SCHEMBL11765051 | 0.75 | NPC1 (0.47) | TSHRTDP1EPHX2PPARGNR2E3 | |
| SCHEMBL11761994 | 0.74 | NPC1 (0.46) | TSHRTDP1EPHX2PPARGNR2E3 | |
| SCHEMBL11764654 | 0.74 | NPC1 (0.46) | TSHRTDP1EPHX2PPARGNR2E3 | |
| SCHEMBL11762812 | 0.74 | NPC1 (0.46) | TSHRTDP1EPHX2PPARGNR2E3 | |
| SCHEMBL3238314 | 0.74 | NPC1 (0.46) | TSHRTDP1EPHX2PPARGNR2E3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0398099-B1 | PROCESS FOR THE PRODUCTION OF CYCLOPENTANONES | BASF Aktiengesellschaft (DE) | 1993-09-22 | — | — | EP | disclosed |
| US-5166447-A | Preparation of cyclopentanones | BASF AKTIENGESELLSCHAFT (DE) | 1992-11-24 | — | — | US | disclosed |
| EP-0398099-A1 | Process for the production of cyclopentanones | BASF Aktiengesellschaft (DE) | 1990-11-22 | — | — | EP | disclosed |