Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | RARB | P10826 | 5/20 | 0.38 |
| ▸ | ACACB | O00763 | 6/20 | 0.37 |
| ▸ | RARA | P10276 | 1/20 | 0.34 |
| ▸ | RARG | P13631 | 1/20 | 0.34 |
| ▸ | THRA | P10827 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.33 |
| ▸ | PTPRO | Q16827 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9511465 | 0.97 | ACACB (0.39) | TSHRHSD17B10MAPTRAB9AL3MBTL1 | |
| SCHEMBL9509905 | 0.96 | HSD17B10 (0.48) | TSHRHSD17B10MAPTRAB9AL3MBTL1 | |
| SCHEMBL9509231 | 0.95 | HSD17B10 (0.50) | TSHRHSD17B10MAPTRAB9AL3MBTL1 | |
| SCHEMBL9509273 | 0.95 | HSD17B10 (0.50) | TSHRHSD17B10MAPTRAB9AL3MBTL1 | |
| SCHEMBL7908263 | 0.94 | HSD17B10 (0.43) | TSHRHSD17B10MAPTRAB9AL3MBTL1 | |
| SCHEMBL9511483 | 0.93 | TSHR (0.44) | TSHRHSD17B10MAPTRAB9AL3MBTL1 | |
| SCHEMBL9510193 | 0.93 | TSHR (0.41) | TSHRHSD17B10MAPTRAB9AL3MBTL1 | |
| SCHEMBL9508755 | 0.92 | HSD17B10 (0.46) | TSHRHSD17B10MAPTRAB9AL3MBTL1 | |
| SCHEMBL9509464 | 0.92 | HSD17B10 (0.46) | TSHRHSD17B10MAPTRAB9AL3MBTL1 | |
| SCHEMBL9508771 | 0.92 | ACACB (0.39) | TSHRHSD17B10ACACBFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0308438-B1 | LIQUID CRYSTAL PHASE CONTAINING TOLANES | MERCK PATENT GmbH (DE) | 1993-09-29 | — | — | EP | disclosed |