SCHEMBL9512936

SCHEMBL9512936

C=CCNc1ccc(NCCCCCC)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABL1 P00519 1/20 0.47
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CA9 Q16790 1/20 0.46
KCNH3 Q9ULD8 1/20 0.42
THRA P10827 1/20 0.42
THRB P10828 1/20 0.42
ACHE P22303 2/20 0.40
BCHE P06276 1/20 0.40
PRSS1 P07477 4/20 0.40
F2 P00734 2/20 0.40
PRSS2 P07478 2/20 0.40
PRSS3 P35030 2/20 0.40
TMPRSS6 Q8IU80 2/20 0.40
ST14 Q9Y5Y6 2/20 0.40
PLK1 P53350 3/20 0.39
FAAH O00519 1/20 0.39
LMNA P02545 1/20 0.38
CYP1A2 P05177 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1240317 0.98 CA12 (0.47) ABL1CA12CA1CA2CA9
SCHEMBL4874435 0.93 CA1 (0.49) ABL1CA12CA1CA2CA9
SCHEMBL9506930 0.84 ABL1 (0.59) ABL1KCNH3PRSS1F2PRSS2
SCHEMBL11476522 0.84 ABL1 (0.59) ABL1KCNH3PRSS1F2PRSS2
SCHEMBL30220137 0.84 ABL1 (0.59) ABL1KCNH3PRSS1F2PRSS2
SCHEMBL187892 0.84 ABL1 (0.59) ABL1KCNH3PRSS1F2PRSS2
SCHEMBL11498100 0.84 ABL1 (0.59) ABL1KCNH3PRSS1F2PRSS2
SCHEMBL16439908 0.84 ABL1 (0.59) ABL1KCNH3PRSS1F2PRSS2
SCHEMBL3395174 0.84 ABL1 (0.59) ABL1KCNH3PRSS1F2PRSS2
SCHEMBL2720066 0.84 ABL1 (0.59) ABL1KCNH3PRSS1F2PRSS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0273418-B1 Heat-sensitive recording material using chromeno compound KANZAKI PAPER MFG CO LTD (JP) 1993-11-24 EP disclosed
EP-0232907-B1 HEAT-SENSITIVE RECORDING MATERIAL KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1991-03-27 EP disclosed
US-4803193-A COLORFASTNESS; READABLE BY OPTICAL CHARACTER-READING DEVICES KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1989-02-07 US disclosed
US-4761396-A BASIC PHTHALIDE DYE REACTS WITH FLUORENE DERIVATIVE AND P-PHENYLENEDIAMINE DERIVATIVE KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1988-08-02 US disclosed
EP-0273418-A2 Heat-sensitive recording material using chromeno compound KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1988-07-06 EP disclosed
EP-0232907-A2 Heat-sensitive recording material KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1987-08-19 EP disclosed